Dr Adrian Fuchs
Research Fellow
Australian Institute for Bioengineering and Nanotechnology
+61 7 334 63849
Journal Articles
Sivaram, Amal J., Wardiana, Andri, Preethi, S. S. Hema, Fuchs, Adrian V., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2020). Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids. Macromolecular Rapid Communications 2000294, e2000294. doi: 10.1002/marc.202000294
Houston, Zachary H., Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B., Fletcher, Nicholas L., Fuchs, Adrian V., Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W., Mahler, Stephen M., Richards, Linda J., Caruso, Frank and Thurecht, Kristofer J. (2020). Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies. ACS Central Science, 6 (5) acscentsci.9b01299, 727-738. doi: 10.1021/acscentsci.9b01299
Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g
Akhter, Dewan T., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Bell, Craig A. and Thurecht, Kristofer J. (2019). Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity. Advanced Therapeutics, 3 (2), 1900171. doi: 10.1002/adtp.201900171
Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Smith, Fiona, Stringer, Brett, Carrington, Benjamin, Fuchs, Adrian, Bell, Craig, Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer, Boyd, Andrew and Day, Bryan (2018). EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma. Cancers, 10 (12) 519, 519. doi: 10.3390/cancers10120519
Chen, Liyu, Simpson, Joshua D, Fuchs, Adrian V, Rolfe, Barbara E and Thurecht, Kristofer J (2017). Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice. Molecular pharmaceutics, 14 (12), 4485-4497. doi: 10.1021/acs.molpharmaceut.7b00611
Pearce, Amanda K., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Russell, Pamela J., Whittaker, Andrew K. and Thurecht, Kristofer J. (2017). Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic. Biomaterials, 141, 330-339. doi: 10.1016/j.biomaterials.2017.07.004
Zhao, Yongmei, Houston, Zachary H., Simpson, Joshua D., Chen, Liyu, Fletcher, Nicholas L., Fuchs, Adrian V., Blakey, Idriss and Thurecht, Kristofer J. (2017). Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranostics. Molecular Pharmaceutics, 14 (10), 3539-3549. doi: 10.1021/acs.molpharmaceut.7b00560
Fuchs, A. V., Bapat, A. P., Cowin, G. J. and Thurecht, K. J. (2017). Switchable 19F MRI polymer theranostics: towards in situ quantifiable drug release. Polymer Chemistry, 8 (34), 5157-5166. doi: 10.1039/c7py00345e
Fuchs, Adrian V. and Thurecht, Kristofer J. (2017). Stability of trithiocarbonate RAFT agents containing both a cyano and a carboxylic acid functional group. ACS Macro Letters, 6 (3), 287-291. doi: 10.1021/acsmacrolett.7b00100
Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies. Advanced Healthcare Materials, 5 (16), 2055-2068. doi: 10.1002/adhm.201600263
Pearce, Amanda K., Fuchs, Adrian V., Fletcher, Nicholas L. and Thurecht, Kristofer J. (2016). Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo. Pharmaceutical Research, 33 (10), 1-12. doi: 10.1007/s11095-016-1945-x
Fuchs, Adrian V., Tse, Brian W.C., Pearce, Amanda. K., Yeh, Mei-Chun, Fletcher, Nicholas L., Huang, Steve S., Heston, Warren D., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2015). Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency. Biomacromolecules, 16 (10), 3235-3247. doi: 10.1021/acs.biomac.5b00913
Ma, Yiming, Fuchs, Adrian V., Boase, Nathan R. B., Rolfe, Barbara E., Coombes, Allan G. A. and Thurecht, Kristofer J. (2015). The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 94, 393-403. doi: 10.1016/j.ejpb.2015.06.014
Fuchs, Adrian V. and Thurecht, Kristofer J. (2015). Interfacial RAFT Miniemulsion Polymerization: Architectures from an Interface. Macromolecular Chemistry And Physics, 216 (12), 1271-1281. doi: 10.1002/macp.201500061
Fuchs, Adrian V., Gemmell, Anna C. and Thurecht, Kristofer J. (2015). Utilising polymers to understand diseases: advanced molecular imaging agents. Polymer Chemistry, 2015 (6), 868-880. doi: 10.1039/c4py01311e
Schach, Denise, Globisch, Christoph, Roeters, Steven J., Woutersen, Sander, Fuchs, Adrian, Weiss, Clemens K., Backus, Ellen H. G., Landfester, Katharina, Bonn, Mischa, Peter, Christine and Weidner, Tobias (2014). Sticky water surfaces: Helix–coil transitions suppressed in a cell-penetrating peptide at the air-water interface. The Journal of Chemical Physics, 141 (22), 22D517.1-22D517.9. doi: 10.1063/1.4898711
Baio, Joe E., Schach, Denise, Fuchs, Adrian V., Schmüser, Lars, Billecke, Nils, Bubeck, Christoph, Landfester, Katharina, Bonn, Mischa, Bruns, Michael, Weiss, Clemens K. and Weidner, Tobias (2014). Reversible activation of pH-sensitive cell penetrating peptides attached to gold surfaces. Chemical Communications, 51, 273-275. doi: 10.1039/C4CC07278B
Pearce, Amanda K., Rolfe, Barbara E., Russell, Pamela J., Tse, Brian W.-C., Whittaker, Andrew K., Fuchs, Adrian V. and Thurecht, Kristofer J. (2014). Development of a polymer theranostic for prostate cancer. Polymer Chemistry, 5 (24), 6932-6942. doi: 10.1039/C4PY00999A
Alexandrino, Evandro M., Buchold, Philipp, Wagner, Manfred, Fuchs, Adrian, Kreyes, Andreas, Weiss, Clemens K., Landfester, Katharina and Wurm, Frederik R. (2014). A molecular "screw-clamp": accelerating click reactions in miniemulsions. Chemical Communications, 50, 10495-10498. doi: 10.1039/C4CC04119D
Fuchs, Adrian V., Kotman, Niklas, Andrieu, Julien, Mailänder, Volker, Weiss, Clemens K. and Landfester, Katharina (2013). Enzyme cleavable nanoparticles from peptide based triblock copolymers. Nanoscale, 5 (11), 4829-4839. doi: 10.1039/c3nr00706e
Fuchs, Adrian V., Ritz, Sandra, Pütz, Sabine, Mailänder, Volker, Landfester, Katharina and Ziener, Ulrich (2013). Bioinspired phosphorylcholine containing polymer films with silver nanoparticles combining antifouling and antibacterial properties. Biomaterials Science, 1 (5), 470-477. doi: 10.1039/c2bm00155a
Fuchs, Adrian V., Walter, Constanze, Landfester, Katharina and Ziener, Ulrich (2012). Biomimetic silver-containing colloids of poly(2-methacryloyloxyethyl phosphorylcholine) and their film-formation properties. Langmuir, 28 (11), 4974-4983. doi: 10.1021/la204673z
Fuchs, Adrian V. and Will, Geoffrey D. (2010). Photo-initiated miniemulsion polymerization as a route to the synthesis of gold nanoparticle encapsulated latexes. Polymer, 51 (10), 2119-2124. doi: 10.1016/j.polymer.2010.03.019
Takami, T., Arnold, D. P., Fuchs, A. V., Will, G. D., Goh, R., Waclawik, E. R., Bell, J. M., Weiss, P. S., Sugiura, K., Liu, W. and Jiang, J. Z. (2006). Two-dimensional crystal growth and stacking of bis(phthalocyaninato) rare earth sandwich complexes at the 1-phenyloctane/graphite interface. Journal of Physical Chemistry B, 110 (4), 1661-1664. doi: 10.1021/jp054739c
Conference Papers
Thurecht, Kristofer, Fuchs, Adrian, Bapat, Abhijeet and Houston, Zachary (2018). Development of polymeric MRI agents as theranostics. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, 18-22 March 2018. Washington, DC United States: American Chemical Society.
Tse, Brian W-C, Pearce, Amanda, Fuchs, Adrian V., Simpson, Joshua D., Yeh, Mei-Chun, Huang, Steve S., Heston, Warren D. W., Williams, Elizabeth D., Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2016). Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31-September 3 2016. United Kingdom: Wiley-Blackwell.
Tse, Brian W-C, Fuchs, Adrian V., Huang, Steve S., Heston, Warren D. W., Yeh, Mei-Chun, Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2015). Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer. 2nd Prostate Cancer World Congress (PCWC), Cairns, Australia, 17-21 August 2015.
Fuchs, Adrian V., Pearce, Amanda K., Tse, Brian W. C., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2014). Multimodal hyperbranched polymers for simultaneous imaging and drug delivery for targeted prostate cancer theranostics. ACS 2014: 247th American Chemical Society National Meeting & Exposition, Dallas, TX, USA, 16-20 March, 2014. Washington, DC, United States: American Chemical Society.
Fuchs, Adrian V., Andrieu, Julien, Kotman, Niklas, Maier, Matthias, Weiss, Clemens and Landfester, Katharina (2012). Versatile methods for the preparation of enzyme cleavable peptide-polymer hybrid nanostructures. 244th National Fall Meeting of the American-Chemical-Society (ACS), Philadelphia, United States, 19-23 August 2012. Washington, United States: American Chemical Society.