Novel solutions for diagnosis and treatment of life-threatening diseases such as cardiovascular and cancerous diseases

Dr Hang Ta is an Australian National Health and Medical Research Council (NHMRC) ECR Fellow at Australian Institute for Bioengineering and Nanotechnology, the University of Queensland. She currently holds joint appointments at Australian Institute for Bioengineering and Nanotechnology and the School of Pharmacy. During her research career, she has been awarded many prizes, grants and prestigious fellowships such as National Heart Foundation and NHMRC ECR fellowships. Her research addresses solutions for current problems in diagnosis and treatment of diseases. She has published papers in journals with high impact factor such as Nature Protocols (Jif: 11.74), Circulation Research (Jif: 13.861), Biomaterials (Jif: 10.1) and Journal of Controlled Release (Jif: 8.078). Her research was highlighted on cover page of Circulation Research, a second-ranked journal in the field of cardiovascular research.

Research Interests

  • Nanosensors for detecting and grading diseases
  • Molecular imaging/Diagnosis of cardiovascular disease
  • Novel nanomaterials for theranostics of cardiovascular, inflammatory, and cancerous diseases
  • Novel reversible blood clotting agents
  • Cardioascular diseases on the chip

Industry Engagement and Collaborations

Dr Hang Ta has established strong collaborations with national and international experts from Baker IDI Heart and Diabetes Institute, Monash University, University of Melbourne, University of Wollongong, Princess Alexandra Hospital, Prince Charles Hospital, Griffith University, Queensland University of Queensland, and Soochow University (China).

Funding

Dr Hang Ta has successfully attained more than $1.4 million funding in the form of grants, fellowships, scholarships and travel awards from NHMRC, National Heart Foundation, Baker IDI Heart and Diabetes Institute, University of Melbourne, University of Queensland, and CASS Foundation.

Key Publications

Ta, Hang T., Arndt, Nina, Wu, Yuao, Lim, Hui Jean, Landeen, Shea, Zhang, Run, Kamato, Danielle, Little, Peter J., Whittaker, Andrew K. and Xu, Zhi Ping (2018) Activatable magnetic resonance nanosensor as a potential imaging agent for detecting and discriminating thrombosis. Nanoscale, 10 31: 15103-15115. doi:10.1039/c8nr05095c. Jif = 8.

Ta, Hang T., Li, Zhen, Hagemeyer, Christoph E., Cowin, Gary, Zhang, Shaohua, Palasubramaniam, Jathushan, Alt, Karen, Wang, Xiaowei, Peter, Karlheinz and Whittaker, Andrew K. (2017) Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast. Biomaterials, 134 31-42. doi:10.1016/j.biomaterials.2017.04.037. Jif = 10.1

Christoph E. Hagemeyer, Karen Alt, Angus P. R. Johnston, Georgina K. Such, Hang T. Ta, Melissa K. M. Leung, Sandeep Prabhu, Xiaowei Wang, Frank Caruso, Karlheinz Peter. 2015. Particle Generation, Functionalization and Sortase A-mediated Modification with Targeting Antibodies for Diagnostic and Therapeutic Use. Nature Protocol, 10, 90-105. Jif = 11.74.

Hang T. Ta; Sandeep Prabhu; Ephraem Leitner; Fu Jia; D. von Elverfeldt; K. Putnam; T. Heidt; A. Nair; H. Pearce; C. von zur Muhlen; X. Wang; K. Peter; C.E. Hagemeyer. 2011. Enzymatic Single-chain Antibody Tagging: A Universal Approach to Targeted Molecular Imaging and Cell Homing in Cardiovascular Disease. Circulation Research, 109, 365-373. Jif = 13.861. (Second ranked journal in Cardiovascular Research field. One image from the publication was selected for the cover of the August 5th issue of Circulation Research. The article was also highlighted on cover page of the journal).

Hang T. Ta, Crispin R. Dass, Ian Larson, Peter Choong, Dave E. Dunstan. 2009. A hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor. Biomaterials, 30, 4815-4823. Jif = 10.1.

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