Response of cells to changes in the mechanical signals of their microenviroment

​In the body, cells reside in a meshwork of protiens that provides support as well as physical and chemical signals. Ian is iinterested in studying the response of cells to changes in the mechanical signals of their microenviroment. To this end, he have developed a hydrogel system with an addition fragmentation-chain transfer crosslinker to allow for photoinduced network reorganization and stress-relaxation. This system will be used to study how cells respond morphologically and genetically to stress-relaxing substrates.

​Ian is a third year Chemical Engineering graduate student from the University of Colorado, Boulder in Kristi Anseth's lab. He isbrining his research project to UQ in Justin Cooper-White's lab on a Whittaker Fellowship. I am also a National Science Foundation Graduate Research Felllow. I graduated with a BS in Biomedical Engineering from the University of Rochester in 2013. 


​Whittaker Fellowship Nationals Science Foundation GRFP

Key Publications

  1. Grim, J.C., Marozas, I.A. and Anseth, K.S., 2015. Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels. Journal of Controlled Release, 219, pp.95-106.​ Azagarsamy, M.A., Marozas, I.A., Spaans, S. and Anseth, K.S., 2015. Photoregulated hydrazone-based hydrogel formation for biochemically patterning 3D cellular microenvironments. ACS Macro Letters, 5(1), pp.19-23.
  2. Brown, T.B., Marozas, I.A., Anseth, K.S. ​Amplified photodegradation of cell-laden hydrogels via an addition-fragmentation chain transfer reaction. Advanced Materials. In Review