Next-generation core–shell materials based on sustainable biomolecular dual-templating

Dr Wibowo's research is at the intersection of chemistry, biology, and chemical engineering. His research is focused on the design, bioproduction, and use of biological molecules to develop sustainable, environmentally friendly approaches for making core–shell structured nanomaterials. A significant portion of the research centers at developing nano–bio interfaces and using biomolecular interactions for interfacial assembly of the biomolecules at soft materials and for the subsequent mineralization of hard materials encapsulating those soft materials. With postgraduate students currently under his supervision, Dr Wibowo's research is projected in a number of directions: (1) An emulsion and biomimetic dual-templating platform technology to manufacture core–shell nanomaterials; (2) Functional nanomaterials for imaging, drug delivery, and controlled release; and (3) An integrated biomolecular and bioprocess platform technology for cost-effective production of biomolecules (e.g. biosurfactants, antimicrobial peptides, mineralizing proteins) in microbial cell factory.

Key Publications

  1. David Wibowo, Guang-Ze Yang, Anton P.J. Middelberg, Chun-Xia Zhao (2016) Non-chromatographic bioprocess engineering of a recombinant mineralizing protein for the synthesis of silica nanocapsules. Biotechnology and Bioengineering (In Press)
  2. David Wibowo, Yue Hui, Anton P.J. Middelberg, Chun-Xia Zhao (2016) Interfacial engineering for silica nanocapsules. Advances in Colloid and Interface Science236, 83–100. 
  3. David Wibowo, Chun-Xia Zhao, Anton P.J. Middelberg (2015) Interfacial biomimetic synthesis of silica nanocapsules using a recombinant catalytic modular protein. Langmuir, 31 (6), 1999–2007.
  4. David Wibowo, Chun-Xia Zhao, Brenton C. Peters, Anton P.J. Middelberg (2014) Sustained release of fipronil insecticide in vitro and in vivo from biocompatible silica nanocapsules. Journal of Agricultural and Food Chemistry, 62 (52), 12504–1251.
  5. David Wibowo, Chun-Xia Zhao, Anton P.J. Middelberg (2014) Emulsion-templated silica nanocapsules formed using bio-inspired silicification. Chemical Communications, 50, 11325–11328. 
Featured projects Duration
Precision nanomaterials based on biomolecule templating