Professor Kirill Alexandrov specialises in next-generation technologies for protein research. 

Professor Kirill Alexandrov obtained his Masters degree in Invertebrate Zoology at the Leningrad State University, Russia in 1989 and completed his PhD in Cell Biology at EMBL Heidelberg, Germany in 1995. He went on to postgraduate work at the Department of Physical Biochemistry at the Max-Planck Institute in Dortmund, Germany, and remained with the Institute for 12 years, becoming a group leader in 1999. In 2004, Professor Alexandrov was awarded Germany’s highest career development fellowship, the Heisenberg Award.

He joined the Institute for Molecular Bioscience (IMB) and The Australian Institute for Bioengineering and Nanotechnology (AIBN) at The University of Queensland in 2008 as an ARC Future Fellow. He introduced high−throughput molecular cloning technology to the UQ Protein Expression Facility.

He holds six active patents all of which are either sold or licenced. Professor Alexandrov has received more than 30 invitations to speak at national and international conferences.

Industry Engagement & Collaborations

Professor Alexandrov co-founded the successful biotechnology company Jena Bioscience GMBH in 1998 and UK/Australian company Molecular Warehouse ltd in 2015. He is credited with establishing the Dortmund Protein Production Facility at the Max-Planck Institute in Dortmund, Germany.

Key Publications

Guo Z, Murphy L, Stein V, Johnston WA, Alcala-Perez S, Alexandrov K. Engineered PQQ-Glucose Dehydrogenase as a Universal Biosensor Platform. J Am Chem Soc. 2016 Aug 17;138(32):10108-11 IF: 11.4 

Cui Z., Stein V., Tnimov Z., Mureev S. and Alexandrov K. Semi-synthetic tRNA complement mediates in vitro protein synthesis. J Am Chem Soc. 2015 Apr 8;137(13):4404-13. IF: 11.4 

Stein V. and Alexandrov K. Protease-based synthetic sensing and signal amplification. Proc Natl Acad Sci U S A.. 2014 Nov 11; 111(45):15934-9 IF: 9.8;  

Mureev S, Kovtun O, Nguyen UT, Alexandrov K. Species-independent translational leaders facilitate cell-free expression. Nature Biotech 2009; 27(8): 747-52. Cover story. . IF: 39.1; Cit.: 47;

Nguyen UT, Guo Z, Delon C, Wu Y, Deraeve C, Fränzel B, Bon RS, Blankenfeldt W, Goody RS, Waldmann H, Wolters D, Alexandrov K. Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nature Chem Biol 2009; 5(4): 227-35. IF: 13.2; Cit.: 70

Full list of publications available at UQ eSpace

Funding

Professor Alexandrov has raised more than $22 million in funding since 2008, securing multiple Australian Research Council(ARC) and National Health and Medical Research Council (NHMRC) grants.

*Joint appointment with UQ’s Institute for Molecular Biosciences. Visit Professor Alexandrov's IMB site here.