Multimodal imaging studies of tumour vasculature remodelling in glioblastoma multiforme.

​My research interest is focused on the study of the effects of tumour vasculature remodelling in the delivery of chemotherapeutic drugs in higher grade gliomas, by use of multimodal imaging techniques, including PET/MRI and optical imaging. In particular I am interested in establishing correlations between in vivo and ex vivo data to explain the phenomena of tumour angiogenesis, blood-brain-barrier disruption and cellular necrosis from a molecular biology perspective.

​Caterina graduated in 2015 from Imperial College of London with first class honours in a MSci. & ARCS in Chemistry with Molecular Physics. During her degree she was granted a Developing Excellence Scheme Sport Scholarship for Swimming at Imperial College London. In 2014 Caterina was awarded a Summer Student Fellowship to conduct a three-months of research program at the Woods Hole Oceanographic Institution in the USA. At the completion of her project she received the David S. Miller Scholarship for Energy and Environmental Science Award and the Imperial College Trust General Funds Conference Funding Grant Award, which allowed her to present her project in at the 2014 AGU Fall Meeting and at the 2015 ASLO Aquatic Science Meeting, respectively. In 2014 Caterina received the GlaxoSmithKline Pharmaceuticals Prize in Practical Organic Chemistry Award and the UROP Summer Poster Prize Winner from the Chemistry Department of Imperial College London. 

In 2015 Caterina received a Medical Research Council Scholarship to complete a MRes degree in Bioimaging Science at Imperial College London, from which she graduated in 2016 with Distinction and the Award for Best Presentation from the MRes in Bioimaging Sciences course 2015-2016 from the Chemistry Department. 

Caterina is an Associate of the Royal College of Science (RCS), an active member of the Royal Society Chemistry (RSC), American Geophysical Union (AGU) and Association for the Science of Limnology and Oceanography (ASLO).

Top 5 Key Publications

​Zhang T, Diaz J, Brighi C, Parsons R, McNally S, Apprill A and Hansel C (2016). Dark production of extracellular superoxide by the coral Porites astreoides and representative symbionts. Front. Mar. Sci. 3:232 (2016). doi: 10.3389/fmars.2016.00232 

Diaz, J. M., C. M. Hansel, A. Apprill, C. Brighi, T. Zhang, L. Weber, S. McNally, L. Xun. Speciesspecific control of extracellular superoxide production by the coral holobiont during a natural bleaching event. Nature Communications, 7:13801 (2016). doi:10.1038/ncomms13801 

Diaz J. M., Hansel C. M., Apprill A., Brighi C., Zhang T., Weber L., McNally S., Xun L. Specieslevel variability in superoxide production by symbiotic corals. Poster session presented by Dr Julia Diaz at: 2016 13th International Coral Reef Symposium; 19-24 June; Honolulu, Hawai'i, USA; 2016. Abstract nr 107. (https://www.sgmeet.com/icrs2016/viewabstract.asp?AbstractID=28193) 

C. Brighi, J. M. Diaz, A. Apprill and C. M. Hansel. Temperature and Light Effects on Extracellular Superoxide Production by Algal and Bacterial Symbionts in Corals: Implications for Coral Bleaching. Poster session presented at: 2015 ASLO Aquatic Science Meeting; 2015 Feb 23–27; Granada. Spain: Association for the Sciences of Limnology & Oceanography; 2015. Abstract nr 506. (http://sgmeet.com/aslo/granada2015/viewabstract.asp?abstractid=25916)  

C. Brighi, J. M. Diaz, A. Apprill and C. M. Hansel. Temperature and Light Effects on Extracellular Superoxide Production by Algal and Bacterial Symbionts in Corals: Implications for Coral Bleaching. Poster session presented at: AGU Fall meeting; 2014 Dec 15–19; San Francisco. California (CA), United States: American Geophysical Union; 2014. Abstract nr 19734. (https://agu.confex.com/agu/fm14/webprogrampreliminary/Paper19734.html)