Microgel formation, and fabrication of tumor spheroids in vitro
Conventional evaluation systems mainly include two-dimensional (2D) cell culture and animal test. 2D cell culture is cheap and quick but can't capture the complexity of the in vivo environment. On the contrary, animal models can provide valuable information but are time-consuming and expensive, and sometimes fail to predict what happens in human body. Microfluidic models which integrate three-dimensional tissue architecture and dynamic flow conditions offer a highly flexible platform for cell culture, creating microenviroment, mimicking organs and blood flows. My project aims to develop 3D in vivo mimicking microfluidic models for evaluating nanoparticle-based cancer therapies.
