Extracellular vesicles, and their potential as a diagnostic tool for breast cancer

​Rebecca's research is focused on extracellular vesicles (EVs), which are a class of circulating biomarker secreted from tumour cells. She is specifically investigating the physical, proteomic and transcriptomic characteristics of breast cancer EVs, and how these relate to tumour characteristics. The aim of this work is to explore whether EVs may represent a promising non-invasive tool for the diagnosis and/or monitoring of breast cancer. 

​Rebecca completed her undergraduate study at the University of Queensland, graduating with a Bachelor of Science (Hons I-Biochemistry) in 2014. She was awarded the Biochemistry Alumni Prize in 2015 as the top performing honours student of the previous year. She commenced her PhD in 2015 with the Centre for Personalised Nanomedicine at the AIBN. 


​Rebecca is co-supervised by A/Prof Michelle Hill, who leads the Precision and Systems Biomedicine group at the QIMR-Berghofer Institute. 

Key Publications

  1. Lane, Rebecca E., Korbie, Darren, Anderson, Will, Vaidyanathan, Ramanathan and Trau, Matt (2015) Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing. Scientific Reports,5 7639.1-7639.7. doi:10.1038/srep07639
  2. Anderson, Will, Lane, Rebecca, Korbie, Darren and Trau, Matt (2015) Observations of tunable resistive pulse sensing for exosome analysis: improving system sensitivity and stability. Langmuir31 23: 6577-6587. doi:10.1021/acs.langmuir.5b01402