Theoretical and computational molecular science: optical tweezers, Brownian dynamics and nonequilibrium systems

​Ann Bui is a postdoctoral research fellow in theoretical and computational molecular science at the Australian Institute for Bioengineering and Nanotechnology with the Bernhardt group.  She focuses on the computational modelling and simulations of nonequilibrium optical tweezers systems to determine the nature of binding energies between cells and substrate. 

​Ann has carried out her studies at the University of Queensland. Prior to her appointment at AIBN, she was researching forces, and the calibration of forces, in optical tweezers.

Key Publications

  1. A. A. M. Bui, A. B. Stilgoe, I. C. D. Lenton, L. J. Gibson, A. V. Kashchuk, S. Zhang, H. Rubinsztein-Dunlop, T. A. Nieminen. (2017). Theory and practice of simulation of optical tweezers. Journal of Quantitative Spectroscopy and Radiative Transfer 195, 66-75.
  2. A. A. M. Bui, A. B. Stilgoe, N. Khatibzadeh, T. A. Nieminen, M. W. Berns, and H. Rubinsztein-Dunlop. (2015). Escape forces and trajectories in optical tweezers and their effect on calibration. Optics Express 23(19), 24317.
  3. N. Khatibzadeh, A. B. Stilgoe, A. A. M. Bui, Y. Rocha, G. M. Cruz, V. L. Y. Loke, L. Z. Shi, T. A. Nieminen, H. Rubinsztein-Dunlop, and M. W. Berns. (2014). Determination of motility forces on isolated chromosomes with laser tweezers. Scientific Reports 4, 6866. 
  4. T. A. Nieminen, N. du Preez-Wilkinson, A. B. Stilgoe, V. L. Y. Loke, A. A. M. Bui, and H. Rubinsztein-Dunlop. (2014). Optical tweezers: theory and modelling. Journal of Quantitative Spectroscopy and Radiative Transfer 146, 59-80.
  5. A. A. M. Bui, A. B. Stilgoe, T. A. Nieminen, H. Rubinsztein-Dunlop. (2013). Calibration of nonspherical particles in optical tweezers using only position measurement. Optics Letters, 38(8), 12446. Selected for Virtual Journal for Biomedical Optics 8(5) 2014.