Dr Janet Reid is the CSIRO-UQ BioFoundry Manager at AIBN

Dr Reid is managing the set up and proof-of-concept phase of the BioFoundry, a new facility located in the Ecosciences Precinct, Dutton Park. The BioFoundry is an initiative in the Synthetic Biology alliance between the Commonwealth Scientific and Industrial Research Organisation (CSIRO) and AIBN, the University of Queensland (UQ). Dr Reid will be assisting researchers with adapting standard bench molecular biology approaches to high-throughput roboticised alternatives. The facility will become nationally available to the research and development community. Access may include residential periods to be trained on equipment use and/or a service-based model. Researchers wishing to make enquires about project suitability and costings can make contact by email to SynBioFoundry@csiro.au.

Dr Reid is an experienced molecular and cell biologist having completed a Bachelor of Science (Microbiology) at the University of Queensland, a Graduate Diploma in Biotechnology at the Queensland University of Technology (QUT), and a PhD at QUT and Mater Research investigating protease cascades, cell surface interactions, and protease-activated receptor activation associated with prostate cancer.

Most recently Dr Reid worked for the Community for Open Antimicrobial Drug Discovery (CO-ADD), a not-for-profit initiative led by academics at the Institute for Molecular Bioscience (IMB), UQ. In this group she developed high-throughput screening protocols for assessing adverse effects of anti-microbial compounds.

Key Publications

He, Y., Reid, J. C., He, H., Harrington, B. S., Finlayson, B., Khan, T., and Hooper, J. D. (2018) Evidence that cell surface localization of serine protease activity facilitates cleavage of the protease activated receptor CDCP1. Biological chemistry 399, 1091-1097 https://dx.doi.org/10.1515/hsz-2017-0308.

Reid, J. C., Matsika, A., Davies, C. M., He, Y., Broomfield, A., Bennett, N. C., Magdolen, V., Srinivasan, B., Clements, J. A., and Hooper, J. D. (2017) Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases. American journal of cancer research 7, 2257-2274

Hill, J. R., Coll, R. C., Sue, N., Reid, J. C., Dou, J., Holley, C. L., Pelingon, R., Dickinson, J. B., Biden, T. J., Schroder, K., Cooper, M. A., and Robertson, A. A. B. (2017) Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors. ChemMedChem 12, 1449-1457 https://dx.doi.org/10.1002/cmdc.201700270.

Reid, J. C., Bennett, N. C., Stephens, C. R., Carroll, M. L., Magdolen, V., Clements, J. A., and Hooper, J. D. (2016) In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B. Biological chemistry 397, 1299-1305 https://dx.doi.org/10.1515/hsz-2016-0163.

Swedberg, J. E., Nigon, L. V., Reid, J. C., de Veer, S. J., Walpole, C. M., Stephens, C. R., Walsh, T. P., Takayama, T. K., Hooper, J. D., Clements, J. A., Buckle, A. M., and Harris, J. M. (2009) Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4. Chemistry & biology 16, 633-643 https://dx.doi.org/10.1016/j.chembiol.2009.05.008.