Dr Linda Harkness
Research Fellow - Stem Cell Bioengi
Australian Institute for Bioengineering and Nanotechnology
+61 7 334 63831
Publications
Book Chapters
Jafari, Abbas, Harkness, Linda, Zaher, Walid and Kassem, Moustapha (2014). Adult stromal (skeletal, mesenchymal) stem cells: advances towards clinical applications. Adult stem cells, stem cell biology and regenerative medicine. (pp. 359-373) edited by Kursad Turksen. New York, NY, United States: Springer Science + Business Media. doi: 10.1007/978-1-4614-9569-7_15
Harkness, Linda and Kassem, Moustapha (2012). Procedures for derivation and characterisation of human embryonic stem cells from Odense, Denmark.. Human Embryonic Stem Cells Handbook. (pp. 33-51) New York, NY United States: Humana Press. doi: 10.1007/978-1-61779-794-1_3.
Harkness, Linda, Prokhorova, Tatyana A., Kassem, Moustapha and Blagoev, Blagoy (2012). Stable isotope labelling with amino acids in cell culture for human embryonic stem cell proteomic analysis. In Kursad Turksen (Ed.), Human embryonic stem cells handbook (pp. 297-305) New York, NY, United States: Springer. doi:10.1007/978-1-61779-794-1_20
Abdallah, Basem M., Harkness, Linda, Mahmood, Amer and Kassem, Moustapha (2011). Direct Differentiation of Human Embryonic Stem Cells toward Osteoblasts and Chondrocytes through an Intermediate Mesenchyme Progenitor Lineage. Embryonic Stem Cells: The Hormonal Regulation of Pluripotency and Embryogenesis. (pp. 607-620) edited by Craig Atwood. Rijeka, Croatia: InTech. doi: 10.5772/15227
Journal Articles
Harkness, Linda, Chen, Xiaoli, Jia, Zhongfan, Davies, Anthony M., Monteiro, Michael, Gray, Peter and Pera, Martin (2019). Fibronectin-conjugated thermoresponsive nanobridges generate three dimensional human pluripotent stem cell cultures for differentiation towards the neural lineages. Stem Cell Research, 38 101441, 101441. doi: 10.1016/j.scr.2019.101441
Vishnubalaji, Radhakrishnan, Elango, Ramesh, Al-Toub, Mashael, Manikandan, Muthurangan, Al-Rikabi, Ammar, Harkness, Linda, Ditzel, Nicholas, Atteya, Muhammad, Hamam, Rimi, Alfayez, Musaad, Aldahmash, Abdullah, Kassem, Moustapha and Alajez, Nehad M. (2019). Neoplastic transformation of human mesenchymal stromal cells mediated via LIN28B. Scientific Reports, 9 (1) 8101, 8101. doi: 10.1038/s41598-019-44536-1
Harkness, Linda, Chen, Xiaoli, Gillard, Marianne, Gray, Peter Paul and Davies, Anthony Mitchell (2019). Media composition modulates human embryonic stem cell morphology and may influence preferential lineage differentiation potential. PLoS ONE, 14 (3) e0213678, e0213678. doi: 10.1371/journal.pone.0213678
Alfaleh, Mohamed, Arora, Neetika, Yeh, Michael, de Bakker, Christopher, Howard, Christopher, Macpherson, Philip, Allavena, Rachel, Chen, Xiaoli, Harkness, Linda, Mahler, Stephen and Jones, Martina (2019). Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning. Antibodies, 8 (1) 15, 15. doi: 10.3390/antib8010015
Jafari, Abbas, Isa, Adiba, Chen, Li, Ditzel, Nicholas, Zaher, Walid, Harkness, Linda, Johnsen, Hans E, Abdallah, Basem M, Clausen, Christian and Kassem, Moustapha (2018). TAFA2 induces skeletal (stromal) stem cell migration through activation of Rac1-p38 signaling. Stem Cells, 37 (3), 407-416. doi: 10.1002/stem.2955
Twine, Natalie A., Harkness, Linda, Adjaye, James, Aldahmash, Abdullah, Wilkins, Marc R. and Kassem, Moustapha (2018). Molecular phenotyping of telomerized human bone marrow skeletal stem cells reveals a genetic program of enhanced proliferation and maintenance of differentiation responses. JBMR plus, 2 (5), 257-267. doi: 10.1002/jbm4.10050
Rumman, Mohammad, Majumder, Abhijit, Harkness, Linda, Venugopal, Balu, Vinay, M. B., Pillai, Malini S., Kassem, Moustapha and Dhawan, Jyotsna (2018). Induction of quiescence (G0) in bone marrow stromal stem cells enhances their stem cell characteristics. Stem Cell Research, 30, 69-80. doi: 10.1016/j.scr.2018.05.010
Chen, Xiaoli, Harkness, Linda, Jia, Zhongfan, Prowse, Andrew, Monteiro, Michael J. and Gray, Peter P. (2018). Methods for expansion of 3D cultures of human embryonic stem cells using a thermoresponsive polymer. Tissue Engineering. Part C. Methods, 24 (3), 146-157. doi: 10.1089/ten.TEC.2017.0331
Prabha, Rahul Damodaran, Kraft, David Christian Evar, Harkness, Linda, Melsen, Birte, Varma, Harikrishna, Nair, Prabha D., Kjems, Jorgen and Kassem, Mousthapha (2017). Bioactive nano-fibrous scaffold for vascularized craniofacial bone regeneration. Journal of Tissue Engineering and Regenerative Medicine, 12 (3), e1537-e1548. doi: 10.1002/term.2579
Burns, Jorge S. , Harkness, Linda , Aldahmash, Abdullah, Gautier, Laurent and Kassem, Moustapha (2017). Chromosome copy number variation in telomerized human bone marrow stromal cells; insights for monitoring safe ex-vivo expansion of adult stem cells. Stem Cell Research, 25, 6-17. doi: 10.1016/j.scr.2017.09.006
Twine, Natalie A., Harkness, Linda, Kassem, Moustapha and Wilkins, Marc R. (2016). Transcription factor ZNF25 is associated with osteoblast differentiation of human skeletal stem cells. BMC Genomics, 17 (1) 872, 872. doi: 10.1186/s12864-016-3214-0
Harkness, Linda, Zaher, Walid, Ditzel, Nicholas, Isa, Adiba and Kassem, Moustapha (2016). CD146/MCAM defines functionality of human bone marrow stromal stem cell populations. Stem Cell Research and Therapy, 7 (1) 4, 4.1-4.13. doi: 10.1186/s13287-015-0266-z
Harkness, Linda., Twine, Natalie A., Abu Dawud, Raed, Jafari, Abbas, Aldahmash, Abdullah, Wilkins, Marc R. and Kassem, Moustapha (2015). Molecular characterization of stromal populations derived from human embryonic stem cells: similarities to immortalized bone marrow derived stem cells. Bone Reports, 3, 32-39. doi: 10.1016/j.bonr.2015.07.002
Tay, Aidan P., Pang, Chi Nam Ignatius, Twine, Natalie A., Hart-Smith, Gene, Harkness, Linda, Kassem, Moustapha and Wilkins, Marc R. (2014). Proteomic validation of transcript isoforms, including those assembled from RNA-Seq data. Journal of Proteome Research, 14 (9), 3541-3554. doi: 10.1021/pr5011394
Pang, Chi Nam Ignatius, Tay, Aidan P., Aya, Carlos, Twine, Natalie A., Harkness, Linda, Hart-Smith, Gene, Chia, Samantha Z., Chen, Zhiliang, Deshpande, Nandan P., Kaakoush, Nadeem O., Mitchell, Hazel M., Kassem, Moustapha and Wilkins, Marc R. (2014). Tools to covisualize and coanalyze proteomic data with genomes and transcriptomes: Validation of genes and Alternative mRNA splicing. Journal of Proteome Research, 13 (1), 84-98. doi: 10.1021/pr400820p
Zaher, Walid, Harkness, Linda, Jafari, Abbas and Kassem, Moustapha (2014). An update of human mesenchymal stem cell biology and their clinical uses. Archives of Toxicology, 88 (5), 1069-1082. doi: 10.1007/s00204-014-1232-8
Sabir, Hardee J., Nehlin, Jan O., Qanie, Diyako, Harkness, Linda, Prokhorova, Tatyana A., Blagoev, Blagoy, Kassem, Moustapha, Isa, Adiba and Barington, Torben (2013). Separate developmental programs for HLA-A and -B cell surface expression during differentiation from embryonic stem cells to lymphocytes, adipocytes and osteoblasts. PLoS One, 8 (1) e54366, e54366.1-e54366.9. doi: 10.1371/journal.pone.0054366
Mahmood, Amer, Harkness, Linda, Abdallah, Basem M., Elsafadi, Mona, Al-Nbaheen, May S., Aldahmash, Abdullah and Kassem, Moustapha (2012). Derivation of stromal (Skeletal and Mesenchymal) stem-like cells from human embryonic stem cells. Stem Cells and Development, 21 (17), 3114-3124. doi: 10.1089/scd.2012.0035
Harkness, Linda, Novikov, Sergey M., Beermann, Jonas, Bozhevolnyi, Sergey I. and Kassem, Moustapha (2012). Identification of abnormal stem cells using raman spectroscopy. Stem Cells and Development, 21 (12), 2152-2159. doi: 10.1089/scd.2011.0600
Taipaleenmaki, Hanna, Harkness, Linda, Chen, Li, Larsen, Kenneth H., Saamanen, Anna-Marja, Kassem, Moustapha and Abdallah, Basem M. (2012). The crosstalk between transforming growth factor-β1 and delta like-1 mediates early chondrogenesis during embryonic endochondral ossification.. Stem Cells, 30 (2), 304-313. doi: 10.1002/stem.792
Harkness, Linda, Mahmood, Amer, Ditzel, Nicholas, Abdallah, Basem M., Nygaard, Jens V. and Kassem, Moustapha (2011). Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential. Bone, 48 (2), 231-241. doi: 10.1016/j.bone.2010.09.023
Aldahmash, Abdullah, Haack-Sorensen, Mandana, Al-Nbaheen, May, Harkness, Linda, Abdallah, Basem M. and Kassem, Moustapha (2011). Human Serum is as Efficient as Fetal Bovine Serum in Supporting Proliferation and Differentiation of Human Multipotent Stromal (Mesenchymal) Stem Cells In Vitro and In Vivo. Stem Cell Reviews and Reports, 7 (4), 860-868. doi: 10.1007/s12015-011-9274-2
Heinonen, J., Taipaleenmaki, H., Roering, P., Takatalo, M., Harkness, L., Sandholm, J., Uusitalo-Jarvinen, H., Kassem, M., Kiviranta, I., Laitala-Leinonen, T. and Saamanen, A. -M. (2011). Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes. Osteoarthritis and Cartilage, 19 (8), 1026-1035. doi: 10.1016/j.joca.2011.04.016
Harkness, Linda, Rasmussen, Iben Anne, Erb, Karin and Kassem, Moustapha (2010). Derivation and characterisation of hESC lines from supernumerary embryos, experience from Odense, Denmark. In Vitro Cellular and Developmental Biology - Animal, 46 (3-4), 259-268. doi: 10.1007/s11626-010-9281-7
Mahmood, Amer, Harkness, Linda, Schroder, Henrik Daa, Abdallah, Basem M. and Kassem, Moustapha (2010). Enhanced differentiation of human embryonic stem cells to mesenchymal progenitors by inhibition of TGF-β/activin/nodal signaling using SB-431542. Journal of Bone and Mineral Research, 25 (6), 1216-1233. doi: 10.1002/jbmr.34
Prokhorova, Tatyana A., Harkness, Linda M., Frandsen, Ulrik, Ditzel, Nicholas, Schroder, Henrik D., Burns, Jorge S. and Kassem, Moustapha (2009). Teratoma formation by human embryonic stem cells is site dependent and enhanced by the presence of Matrigel. Stem Cells and Development, 18 (1), 47-54. doi: 10.1089/scd.2007.0266
Harkness, Linda, Taipaleenmaki, Hanna, Mahmood, Amer, Frandsen, Ulrik, Saamanen, Anna-Marja, Kassem, Moustapha and Abdallah, Basem M. (2009). Isolation and differentiation of chondrocytic cells derived from human embryonic stem cells using dlk1/FA1 as a novel surface marker. Stem Cell Reviews and Reports, 5 (4), 353-368. doi: 10.1007/s12015-009-9099-4
Gjerstorff, Morten F., Harkness, Linda, Kassem, Moustapha, Frandsen, Ulrik, Nielsen, Ole, Lutterodt, Melissa, Mollgard, Kjeld and Ditzel, Henrik J. (2008). Distinct GAGE and MAGE-A expression during early human development indicate specific roles in lineage differentiation. Human Reproduction, 23 (10), 2194-2201. doi: 10.1093/humrep/den262
Harkness, Linda, Christiansen, Helle, Nehlin, Jan, Barington, Torben, Andersen, Jens S. and Kassem, Moustapha (2008). Identification of a membrane proteomic signature for human embryonic stem cells independent of culture conditions. Stem Cell Research, 1 (3), 219-227. doi: 10.1016/j.scr.2008.06.001
Fletcher, Judy M., Ferrier, Patricia M., Gardner, John O., Harkness, Linda, Dhanjal, Seema, Serhal, Paul, Harper, Joyce, Delhanty, Joy, Brownstein, David G., Prasad, Yogesh R., Lebkowski, Jane, Mandalam, Ram, Wilmut, Ian and De Sousa, Paul A. (2006). Variations in humanized and defined culture conditions supporting derivation of new human embryonic stem cell lines. Cloning and Stem Cells, 8 (4), 319-334. doi: 10.1089/clo.2006.8.319
Dawson, Andrew J., King, Tim J., Wilmut, Ian, Harkness, Linda M., Kelly, Brian G. and Rhind, Susan M. (2004). Immunohistochemical characterization of cloned lamb nephropathy. Journal of Histochemistry and Cytochemistry, 52 (12), 1657-1664. doi: 10.1369/jhc.4A6367.2004
Zhu, J., King, T., Dobrinsky, J., Harkness, L., Ferrier, T., Bosma, W., Schreier, L. L., Guthrie, H. D., DeSousa, P. and Wilmut, I. (2003). In vitro and in vivo developmental competence of ovulated and in vitro matured porcine oocytes activated by electrical activation. Cloning and Stem Cells, 5 (4), 355-365. doi: 10.1089/153623003772032853
Gao, Shaorong, McGarry, Michelle, Priddle, Helen, Ferrier, Tricia, Gasparrini, Bianca, Fletcher, Judy, Harkness, Linda, De Sousa, Paul, McWhir, Jim and Wilmut, Ian (2003). Effects of donor oocytes and culture conditions on development of cloned mice embryos. Molecular Reproduction and Development, 66 (2), 126-133. doi: 10.1002/mrd.10300
Rhind, SM, King, TJ, Harkness, LM, Bellamy, C, Wallace, W, DeSousa, P and Wilmut, I (2003). Cloned lambs - lessons from pathology. Nature Biotechnology, 21 (7), 744-745. doi: 10.1038/nbt0703-744
Gao, Shaorong, McGarry, Michelle, Ferrier, Tricia, Pallante, Benedetta, Gasparrini, Bianca, Fletcher, Judy, Harkness, Linda, De Sousa, Paul, McWhir, Jim and Wilmut, Ian (2003). Effect of cell confluence on production of cloned mice using an inbred embryonic stem cell line. Biology of Reproduction, 68 (2), 595-603. doi: 10.1095/biolreprod.102.005819
Gao, Shaorong, Gasparrini, Bianca, McGarry, Michelle, Ferrier, Tricia, Fletcher, Judy, Harkness, Linda, De Sousa, Paul and Wilmut, Ian (2002). Germinal vesicle material is essential for nucleus remodeling after nuclear transfer. Biology of Reproduction, 67 (3), 928-934. doi: 10.1095/biolreprod.102.004606
King, T J, Dobrinsky, J R, Zhu, J, Finlayson, H A, Bosma, W, Harkness, L, Ritchie, W A, Travers, A, McCorquodale, C, Day, B N, Dinnyés, A, De Sousa, P A and Wilmut, I (2002). Embryo development and establishment of pregnancy after embryo transfer in pigs: coping with limitations in the availability of viable embryos. Reproduction (Cambridge, England), 123 (4), 507-15.
King, T. J., Dobrinsky, J. R., Zhu, J., Finlayson, H. A., Bosma, W., Harkness, L., Ritchie, W. A., Travers, A., McCorquodale, C., Day, B. N., Dinnyes, A., De Sousa, P. A. and Wilmut, I. (2002). Embryo development and establishment of pregnancy after embryo transfer in pigs: coping with limitations in the availability of viable embryos. Reproduction, 123 (4), 507-515. doi: 10.1530/rep.0.1230507
De Sousa, P. A., Dobrinsky, J. R., Zhu, J., Archibald, A. L., Ainslie, A., Bosma, W., Bowering, J., Bracken, J., Ferrier, P. M., Fletcher, J., Gasparrini, B., Harkness, L., Johnston, P., Ritchie, M., Ritchie, W. A., Travers, A., Albertini, D., Dinnyes, A., King, T. J. and Wilmut, I. (2002). Somatic cell nuclear transfer in the pig: Control of pronuclear formation and integration with improved methods for activation and maintenance of pregnancy. Biology of Reproduction, 66 (3), 642-650. doi: 10.1095/biolreprod66.3.642
De Sousa, Paul A., King, Tim, Harkness, Linda, Young, Lorraine E., Walker, Simon K. and Wilmut, Ian (2001). Evaluation of gestational deficiencies in cloned sheep fetuses and placentae. Biology of Reproduction, 65 (1), 23-30. doi: 10.1095/biolreprod65.1.23
Campbell, B. K., Engelhardt, H., McNeilly, A. S., Harkness, L. M., Fukuoka, M. and Baird, D. T. (1999). Direct effects of ovine follicular fluid on ovarian steroid secretion and expression of markers of cellular differentiation in sheep. Journal of Reproduction and Fertility, 117 (2), 259-269.
Baird, DT, Webb, R, Campbell, BK, Harkness, LM and Gosden, RG (1999). Long-term ovarian function in sheep after ovariectomy and transplantation of autografts stored at -196 C. Endocrinology, 140 (1), 462-471. doi: 10.1210/en.140.1.462
Harkness, LM and Baird, DT (1997). Morphological and molecular characteristics of living human fetuses between Carnegie stages 7 and 23: Developmental stages in the post-implantation embryo. Human Reproduction Update, 3 (1), 3-23. doi: 10.1093/humupd/3.1.3
Harkness, LM and Baird, DT (1997). Morphological and molecular characteristics of living human fetuses between Carnegie stages 7 and 23: Localization of inhibin mRNA α and βa subunits by in-situ hybridization. Human Reproduction Update, 3 (1), 59-78. doi: 10.1093/humupd/3.1.59
Harkness, LM and Baird, DT (1997). Morphological and molecular characteristics of living human fetuses between Carnegie stages 7 and 23: Immunolocalization of inhibin α and βa subunits. Human Reproduction Update, 3 (1), 35-57. doi: 10.1093/humupd/3.1.35
Harkness, LM, Rodger, M and Baird, DT (1997). Morphological and molecular characteristics of living human fetuses between Carnegie stages 7 and 23: Ultrasound scanning and direct measurements. Human Reproduction Update, 3 (1), 25-33. doi: 10.1093/humupd/3.1.25
Harkness, LM and Baird, DT (1997). Appendix: Morphological and molecular characteristics of living human fetuses between Carnegie stages 7 and 23: Embryos in the collection. Human Reproduction Update, 3 (1), 79-92. doi: 10.1093/humupd/3.1.79
Engelhardt H., Harkness L.M., Thomas G.B., Brooks A.N., McNeilly A.S. and Baird D.T. (1995). Expression of inhibin α- and βA-subunit mRNA and protein in the fetal sheep ovary throughout gestation. Molecular and Cellular Endocrinology, 107 (2), 141-147. doi: 10.1016/0303-7207(94)03435-V
Wallace, E M, Harkness, L M, Burns, S and Liston, W A (1994). Evaluation of maternal serum immunoreactive inhibin as a first trimester marker of Down's syndrome. Clinical endocrinology, 41 (4), 483-6.
Wallace, Euan M., Harkness, Linda M., Burns, Sheila and Liston, William A. (1994). Evaluation of maternal serum immunoreactive inhibin as a first trimester marker of Down's syndrome. Clinical Endocrinology, 41 (1), 483-486. doi: 10.1111/j.1365-2265.1994.tb02579.x
Angell, R. R., Ledger, W., Yong, E. L., Harkness, L. and Baird, D. T. (1991). Cytogenetic Analysis of Unfertilized Human Oocytes. Human Reproduction, 6 (4), 568-573.
Conference Papers
Harkness, Linda, Chen, Xiaoli, Davies, Anthony M., Jia, Zhongfan, Monteiro, Michael J., Pera, Martin and Gray, Peter P. (2016). 3D neuronal differentiation: using a thermo-responsive polymer for expansion and release of differentiated hESC. EMBO/EMBL Symposium: Organoids: Modelling organ development and disease in 3D culture, Heidelberg, Germany, 12-15 October 2016.
Harkness, Linda, Chen, Xiaoli, Davies, Anthony M., Jia, Zhongfan, Monteiro, Michael J., Pera, Martin and Gray, Peter P. (2016). 3D neuronal differentiation: using a thermo-responsive polymer for expansion and release of differentiated hESC. Conference on Changing the Face of Modern Medicine - Stem Cells and Gene Therapy, Florence, Italy, 18-21 October 2016. New Rochelle, NY, United States: Mary Ann Liebert.
Harkness, Linda, Chen, Xiaoli, Gray, Peter P. and Davies, Anthony M. (2016). Methods and analysis of pluripotency markers and cell viability in hESC cultured as 3D aggregates. 14th Annual Meeting of the International Society for Stem Cell Research, San Francisco, CA, United States, 22-25 June 2016.
Harkness, Linda, Rumman, Mohammad, Dhawan, Jyotsna and Kassem, Moustapha (2014). Establishing quiescence in human bone marrow stromal stem cells leads to enhanced osteoblast marker expression. International Society for Stem Cell Research (ISSCR) 12th Annual Meeting, Vancouver, BC Canada, 18-21 June 2014. Vancouver, BC Canada: ISSCER.
Tay, Aidan, Pang, Chi, Twine, Natalie, Harkness, Linda, Hart-Smith, Gene, Kassem, Moustapha and Wilkins, Mare (2014). Validation of transcripts assembled from RNA-seq data using proteomics data. International Conference on Bioinformatics (INCOB), Sydney, NSW, Australia, 31 July - 2 August 2014.
Harkness, L., Dawud, R. A., Jafari, A., Adjaye, J. and Kassem, M. (2012). Derivation of human stromal (skeletal) stem (MSC)-like cells from embryonic stems with similar molecular signature to bone marrow derived MSC. 39th Annual Congress of the European-Calcified-Tissue-Society (ECTS), Stockholm Sweden, May 19-23, 2012. ELSEVIER SCIENCE INC. doi: 10.1016/j.bone.2012.02.228
Abdallah, Basem, Harkness, Linda, Taipaleenmaki, Hanna and Kassem, Moustapha (2011). 1(st) IOF-ESCEO Pre-Clinical Symposium. 1st IOF-ESCEO Pre-Clinical Symposium, Valencia Spain, Mar 23-26, 2011. LONDON: SPRINGER LONDON LTD. doi: 10.1007/s00198-011-1564-7
Harkness, Linda , Taipaleenmaki, Hanna , Saamanen, Ann-Marie , Kassem, Moustapha and Abdallah, Basem M. (2011). TGFb signalling inhibits DLK1 expression during chondrogenesis in vitro. 9th Annual Meeting of the International Society for Stem Cell Research, Toronto/Metro Toronto Convention Centre, 15-18 June 2011.
Hardee Sabir, Adiba Isa, Jan Nehlin, Diakyo W Qanie, Linda Harkness, Tatyana Prokhorova, Moustapha Kassem and Torben Barrington (2011). Separate developmental programs for HLA-A and -B expression during diffenrentiation from embryonic stem cells to lymphocytes, adipocytes and osteocytes. Åben Forsker Dag, Fredericia, Denmark, 28 April 2011.
Abdallah, Basem, Harkness, Linda, Taipaleenmaki, Hanna and Kassem, Moustapha (2011). DLK1/FA1 regulates the early chondrogenesis during embryonic endochondral bone formation process and its expression is modulated by TGF-beta 1 signaling pathway. First IOF-ESCEO Pre-Clinical Symposium, Valencia, Spain, 23 - 26 March 2011. London, United Kingdom: Springer U K.
Linda Harkness, Amer Mahmood, Nicholas Ditzel, Basem M Abdallah, Jens V Nygaard and Moustapha Kassem (2010). Selective Isolation and Differentiation of a Stromal Population of Human Embryonic Stem Cells with Osteogenic Potential. European Calcified tissue Society, Glasgow, Scotland, 23-26 June 2010.
Novikov S.M., Beermann J., Bozhevolnyi S.I., Harkness L.M. and Kassem M. (2010). Raman microscopy of individual living human embryonic stem cells. Biophotonics: Photonic Solutions for Better Health Care II, Brussels, April 12, 2010-April 16, 2010. SPIE-INT SOC OPTICAL ENGINEERING. doi: 10.1117/12.854207
Basem M Abdallah, Linda Harkness, Jan Nehlin, Torben Barrington, Jens S Andersen and Moustapha Kassem (2009). Dlk1/FA1 is a novel marker for chondrocyte differentiation during endochondral bone development and chondrogenic lineage progression of human embryonic stem cells. 7th Annual Meeting of the International Society for Stem Cell Research, Barcelona Spain, 8-11 July 2009.
Linda Harkness, Amer Mahmood, Nicholas Ditzel, Basem M Abdallah and Moustapha Kassem (2009). Derivation of hESC and Differentiation to Osteoblast Cells. Danish Stem Cell Doctoral School Annual Meeting, Odense, Denmark, 13-16 June 2009.
Abdallah, Basem M., Harkness, Linda and Kassem, Moustapha (2008). Dlk1/FA1 regulates the chondrogenic condensation and early chondrocyte differentiation in limb bud micromass cultures and its expression is modulated by TGF-beta signaling pathway. European Calcified Tissue Society, Barcelona, Spain, 24-28 May 2008. Oxford, United Kingdom: John Wiley & Sons.
Linda Harkness, Helle Christiansen, Jan Nehlin, Torben Barrington, Jens S Andersen and Moustapha Kassem (2008). Identification of a Membrane proteomic signature for human embryonic stem cells independent of culture conditions. Beta Cells Therapy Course, Copenhagen, Denmark, 28-30 May 2008.
Lijin Zou, Xuenong Zou, Haisheng Li, Weimin Qiu, Linda Harkness, Moustapha Kassem and Cody Bunger (2008). SPONTANEOUS TRANSFORMATION OF CULTURED PORCINE BONE MARROW STROMAL CELLS. European Federation of National Associations of Orthopaedics and Traumatology, Aarhus, Denmark, 7-9 May 2008.
Linda Harkness and Moustapha Kassem (2008). Differentiation of human embryonic stem cells to osteoblastic cells. DASDOC/DSCS, Sønderborg, Denmark, 3-5 November 2008.
Abdallah, B. M., Harkness, L. M., Taipaleenmaki, H., Frandsen, U., Mahmood, A., Jensen, C. H., Saamanen, A. and Kassem, M. (2008). Dlk1/FA1 is a novel marker for chondrocyte differentiation during endochondral bone development and chondrogenic lineage progression of human embryonic stem cells. NEW YORK: SPRINGER.
Linda Harkness, Karen Erb, Nicholas Ditzel, Tatyana Prokhorova, Ulrik Frandsen and Moustapha Kassem (2007). Derivation and characterisation of human embryonic stem cell lines on human and mouse fibroblasts in Odense, Denmark. 5th Annual Meeting of the International Society for Stem Cell Research, Cairns, Australia, 15-20 June 2007.
Linda Harkness, Amer Mahmood, Basem M. Abdallah and Moustapha Kassem (2007). Characterisation and osteoblast induction of a sub-population of human embryonic stem cells with mesenchymal stem cell-like characteristics. 5th Annual Meeting of the International Society for Stem Cell Research, Cairns Convention Centre, Cairns, Australia, 15-20 June 2007.
Rasmussen, I. A. and Harkness, L. (2007). How many IVF-derived spare embryos are needed for establishing one embryonic stem cell line. TAYLOR & FRANCIS AS.
Tatyana Prokhorova, Linda Harkness, Nicholas Ditzel, Ulrik Frandsen, Jorge Burns and Moustapha Kassem (2006). New Danish embryonic stem cell lines derivation and characterisation. Evaluatio n of teratoma formation after transplantation into different sites in NOD/SCID immune deficient mice. 4th Annual Meeting of the International Society for Stem Cell Research, Toronto/Metro Toronto Convention Centre, 24-28 August 2006.
Rasmussen, Iben-Ann and Harkness, Linda (2006). How many IVF derived spare embryos are needed for establishing one embryonic stem cell line. XVII Nordic IVF Meeting, Espoo, Finland, 4-6 August. Acta Obstetrica et Gynecologica Scandinavica:
Gao, SR, McGarry, M, Ferrier, T, Pallante, B, Gasparrini, B, Fletcher, J, Harkness, L, De Sousa, P, McWhir, J and Wilmut, I (2002). Mice cloned from inbred embryonic stem cells.. SOC STUDY REPRODUCTION.
Campbell, BK, Harkness, LM, Armstrong, DG, Garverick, HA, Webb, R and Baird, DT (1998). Expression of markers of differentiated cell function in the ovarian follicles of sheep carrying the FecB gene.. SOC STUDY REPRODUCTION.
Seminar Paper
Linda Harkness (2010). Derivation of hESC and Differentiation to Osteoblast Cells. Geron Biotechnology, Menlo Park, CA, USA.
Video Document
Working Paper
Adler, Sara, Allsopp, Timothy, Bremer, Susanne, Buzanska, Leonora, Drake, Rosemary, Frandsen, Ulrik, Gribaldo, Laura, Gmeiner, Karin, Harkness, Linda, Hartung, Thomas, Healy, Lyn, Hescheler, Jurgen, Knaut, Holger, Mandenius, Carl-Fredrik, Pazos, Patricia, Price, Anna, Pellizzer, Cristian, Pera, Martin, Reubinoff, Benjamin, Stojanov, Tomas, Strehl, Raimund, Stummann, Tina, Trosko, James, Hasiwa, Marina and Stacey, Glyn (2007). hESC Technology for Toxicology and Drug Development: Summary of Current Status and Recommendations for Best Practice and Standardization The Report and Recommendations of and ECVAM Workshop.. ECVAM Workshop Report. European Center for theValidation of Alternative Methods.