Project Summary

In this project we examine and manipulate novel epigenetic marks that track with functional  and transcriptional maturation of mouse and human neurons derived from pluripotent stem cells in order to understand their role(s)  in maturation of these cells. 

Mouse neurons labelled with synaptic markers

 

Research Group

Wolvetang Group

Keywords

iPSC, Reprogramming, differentiation, epigenetics, Ageing, neurons, organoids, CRISPR

Student projects

Functional gRNA screens for epigenetic determinants of neuronal maturation

Project members

Lead Investigator


Professor Ernst Wolvetang

Senior Group Leader
Wolvetang Group
UQ-StemCARE Director

Researchers Involved


Dr Sally Martin

Senior Research Fellow
Wolvetang Group