Epigenetic and functional maturation of iPSC derived neuronal cells
Duration:
January 2017–January 2019
Project Summary
In this project we examine and manipulate novel epigenetic marks that track with functional and transcriptional maturation of mouse and human neurons derived from pluripotent stem cells in order to understand their role(s) in maturation of these cells.
Research Group
Keywords
iPSC, Reprogramming, differentiation, epigenetics, Ageing, neurons, organoids, CRISPR
Student projects
Functional gRNA screens for epigenetic determinants of neuronal maturation
