Project summary

Microfluidic platforms hold great promise for sensitive and early detection of cancer in a resource limited environment. These devices coupled with electrochemical detection have become an enabling technology for point-of-care and personalised diagnostics due to its capabilities of simplicity, portability, low cost and their performance of multiplexed and quantitative measurements, ideally in a high-throughput format.

In this project, we fabricate microfluidic devices that contain asymmetric electrodes. The electrodes will be used to sense a broad range of cancer relevant biomarkers (e.g., proteins, DNA, RNA, cells) in biological and clinical samples.

Students will achieve hands-on experience in the application of the microfluidic devices and electrochemical microbiosensors for cancer diagnostics.

Illustration of a microfluidic device for exosome detection (for details, see Analytical Chemistry 86, 11125-11132)

Research Group

Trau Group


Biosensors, microfluidics, microfabrication, electrochemical detection, cancer biomarker

Available Student Projects

DNA microdevices for Cancer Detection, A new interfacial bio-sensing approach for detecting aberrant protein phosphorylation in cancer

Project members

Lead Investigator

Professor Matt Trau

Senior Group Leader
Trau Group


Dr Alain Wuethrich

NHMRC Emerging Leadership Fellow and ARC DECRA awardee
Centre for Personalised Nanomedicine (Trau Group)