Project summary

Microfluidic platforms hold great promise for sensitive and early detection of cancer in a resource limited environment. These devices coupled with electrochemical detection have become an enabling technology for point-of-care and personalised diagnostics due to its capabilities of simplicity, portability, low cost and their performance of multiplexed and quantitative measurements, ideally in a high-throughput format.

In this project, we fabricate microfluidic devices that contain asymmetric electrodes. The electrodes will be used to sense a broad range of cancer relevant biomarkers (e.g., proteins, DNA, RNA, cells) in biological and clinical samples.

Students will achieve hands-on experience in the application of the microfluidic devices and electrochemical microbiosensors for cancer diagnostics.

Illustration of a microfluidic device for exosome detection (for details, see Analytical Chemistry 86, 11125-11132)

Research Group

Trau Group

Keywords

Biosensors, microfluidics, microfabrication, electrochemical detection, cancer biomarker

Available Student Projects

DNA microdevices for Cancer Detection, A new interfacial bio-sensing approach for detecting aberrant protein phosphorylation in cancer

Project members

Lead Investigator


Professor Matt Trau

Senior Group Leader
Trau Group