• Professor Alan Rowan


    Telephone: +61 7 334 64305 Email: aibn.director@uq.edu.au


    BSc University of Liverpool, PhD University of Liverpool, FRSC
    AIBN Director and Group Leader

    Professor Alan Rowan has performed his research at the interface of chemistry and biology with seminal and pioneering work on processive catalysis and functional self-assembly. His latest scientific achievement has been the development of the first truly biomimetic hydrogel which mimics the mechanic and functional properties of the extracellular membrane. This recent discovery has further established Professor Rowan as a truly innovative scientist, working toward understanding at the molecular level the functional of hierarchical materials and catalysis.

    Professor Rowan’s considerable scientific curiosity has resulted in him working in many areas, ranging from magnetic materials, single enzyme catalysis, supramolecular catalysis through to nanometer-sized solar cells and photonic materials. In the last ten years he developed the concept of processive catalysis, mimicking the natural exo- and endonucleases and demonstrated that a macrocyclic catalyst can thread onto and move along a polymer substrate in a highly efficient process. Demonstrating that such a process was possible, led Prof Rowan to study more precisely the physical chemistry of the process.

    In the last three years Professor Rowan has been intrigued by the complex relationship between the architecture and mechanical properties of the extracellular matrix and its interaction with cells and proteins. His group developed the first truly biomimetic hydrogel, which mimics precisely the mechanical behaviour of the natural fibrous materials. This work has received considerable attention since it is the first step to truly controlling cell behaviour. This scientific breakthrough is already now being developed commercial for wound dressing, drug therapeutic and cell growth.

    Professor Rowan has published nearly 300 hundred peer-reviewed articles and books which were cited 12,000 times. He has had the pleasure of supervising more than 45 PhDs students who have received their doctoral degree.

  • Professor Debra Bernhardt
    BSc (Hons 1) Newcastle, PhD Newcastle, FRACI
    Group Leader


    Telephone: +61 7 334 63939 Email: d.bernhardt@uq.edu.au

    Research: Theoretical and computational molecular science: nonequilibrium systems, fluids and materials

    Professor Debra Bernhardt is internationally recognised for her contributions to the development of nonequilibrium statistical mechanics and thermodynamics including far-from-equilibrium fluids and confined fluids. She is a Fellow of the Royal Australian Chemical Institute and Director of the AIBN Centre for Theoretical and Computational Molecular Science. Professor Bernhardt’s 20 years of research experience includes appointments at the University of Basel, Switzerland; the Australian National University; and Griffith University, where she was founding director of the Queensland Micro- and Nanotechnology Centre. Professor Bernhardt's research interests focus on the use of a range of theoretical and computational approaches to develop a fundamental understanding of the behaviour of matter, and application of these approaches to a wide range of problems including transport in nanopores, fluctuation phenomena, design of materials, gas separation, energy storage and conversion.

    International links

    Professor Bernhardt has held a research appointment at the University of Basel in Switzerland. She has recently had strong international collaborations with researchers at Politecnico di Torino, Italy; The University of Sheffield, UK; University of Leipzig, Germany; and École Normale Supérieure, France.

    Memberships and funding

    Professor Bernhardt is a Fellow of the Royal Australian Chemical Institute. She has has three current Australian Research Council (ARC) funding grants and has received ARC grant funding of more than $6.5 million since 1998. She has been involved in organisation of a number of conferences including Nonequilibrium Processes: the Last 40 years and the Future in Obergurgl, Austria in 2011; 1st Australian-Italian Workshop on Statistical Physics on the Gold Coast in 2006; and International Union of Pure and Applied Chemistry’s World Chemistry Congress 2001. She is co-chair of Molecular Modelling 2014, which will be held in Queensland.

    Awards and plenaries

    Professor Bernhardt has been plenary, keynote or invited speaker at many international conferences including the Joint European Thermodynamics Conference, (Brescia, Italy, 2013) Workshop on Small System Nonequilibrium Fluctuations (ICITP, Beijing, 2013); Fluid-Structure Interactions in Soft-Matter Systems: From the Mesoscale to the Macroscale (Prato, Italy, 2012); Gordon conference on the Chemistry and Physics of Liquids (New Hampshire, US, 2011); StatPhys-Kolkata VII (SINP, Kolkata, India, 2010); and the Warwick EPSRC Symposium on Challenges in Scientific Computing (University of Warwick, UK, 2009). In 2011, while at Griffith University, Professor Bernhardt was awarded the Vice Chancellor’s Research Excellence Award for Research Leadership. She is the recipient of the 2004 Australian Journal of Chemistry Award for Innovative Work in Physical Chemistry by a Younger Scientist.

    Recent Publications

    Professor Bernhardt publishes using her maiden name, Debra J Searles. Full list of publications available at UQ eSpace.

  • Professor Justin Cooper-White, above, and his research on meniscus regeneration explained, below.
    BE (Chem) (Hons) UQ, PhD UQ
    Group Leader


    Telephone: +61 7 334 63858 Email: j.cooperwhite@uq.edu.au

    Research: Elucidating the microenvironmental cues that regulate stem cell behaviours and translating those insights into biomaterial scaffolds and microdevices to direct stem cell differentiation

    Professor Justin Cooper-White is a global leader in using engineering to solve problems in biology. In addition to holding the position of AIBN Group Leader, Professor Cooper-White is Director of the Australian National Fabrication Facility-Queensland Node and is one of only 13 CSIRO Office of the Chief Executive Science Leaders across the country. He is a past President of both the Australasian Society for Biomaterials and Tissue Engineering and the Australian Society of Rheology and has previously served as an Associate Dean (Research) at the UQ Faculty of Engineering, Architecture and Information Technology.

    International links

    Professor Cooper-White has many past and currently active international collaborations with world leading research groups at MIT (US); Stanford (USA); ETH (Switzerland); EPFL (Switzerland); SNU (Korea); University Of Grenoble (France); Politecnico di Milano (Italy); UCL (UK); and the Max Planck Institute (Germany). He has performed contract research and consultancy work for Unilever in the UK; Nestle International, Switzerland; Rhodia, US; Inion, Finland since 2001 and a Queensland primary business. He has previously held a Visiting Professor Fellowship (2007) at ETH Zurich and a Politecnico di Milano Visiting Professor Fellowship (2012-2013). He is the associate editor of the Korean-Australian Rheology Journal; serves or has served on the editorial boards of Biomaterials Science, Rheological Acta, Soft Materials, Biomicrofluidics and the Open Biomedical Engineering Journal; and is a reviewer of major international journals, including Nature Methods, Advanced Materials, Lab on a Chip, Stem Cells, Stem Cells and Development, Biomacromolecules, Tissue Engineering, Langmuir, Biomaterials and Journal of Non-Newtonian Fluid Mechanics.

    Memberships, patents and funding

    Professor Cooper-White has been chair or co-chair of three international conferences, focusing on either rheology or biomaterials and tissue engineering: the Australian representative on the International Advisory Committee, 15th International Congress on Rheology, Monterey, US; a member of the International Scientific Advisory Committee for the World Congress on Biomaterials, Amsterdam, Netherlands; and currently an Australian representative on the Interntional Union of Societies for Biomaterials Science and Engineering (IUSBE). He is the inventor on six international patents. He has performed contract and sponsored research work for multinationals such as Mesoblast, Rhodia, Unilever and Nestle International and has received more than $45 million in competitive grant funding.

    Awards and plenaries

    Recognition of Professor Cooper-White’s standing in the research field is reflected in the nine plenary and more than 25 keynote presentations he has been invited to give at national and international conferences since 2001. He received the 2005 Annual Award of the British Society of Rheology for contributions to the fields of rheology and non-Newtonian fluid mechanics. His work on engineered surfaces, specifically for directing mesenchymal stem cell fate was highlighted as one the most influential works on stem cell – biomaterial interactions at the 2008 World Biomaterials Congress in Amsterdam, the Netherlands.

    Key publications in the past five years

    The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells
    Cameron, Andrew R., Frith, Jessica E., Gomez, Guillermo A., Yap, Alpha S and Cooper-White, Justin J. (2014) The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells. Biomaterials, 35 6: 1857-1868.

    Modulation of stem cell adhesion and morphology via facile control over surface presentation of cell adhesion molecules
    Li, Haiqing, Frith, Jessica and Cooper-White, Justin J. (2014) Modulation of stem cell adhesion and morphology via facile control over surface presentation of cell adhesion molecules. Biomacromolecules, 15 1: 43-52.

    Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration
    Frith, Jessica E., Menzies, Donna J., Cameron,Andrew R., Ghosh, P., Whitehead, Darryl L., Gronthos, S., Zannettino, Andrew C.W. and Cooper-White, Justin J. (2014) Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration. Biomaterials, 35 4: 1150-1162.

    Effects of cell density and biomacromolecule addition on the flow behavior of concentrated mesenchymal cell suspensions
    Maisonneuve, Benoît G. C., Roux, Denis C. D., Thorn, Peter and Cooper-White, Justin J. (2013) Effects of cell density and biomacromolecule addition on the flow behavior of concentrated mesenchymal cell suspensions. Biomacromolecules, 14 12: 4388-4397.

    Microbioreactor array screening of Wnt modulators and microenvironmental factors in osteogenic differentiation of Mesenchymal progenitor cells
    Frith, Jessica E., Titmarsh, Drew M., Padmanabhan, Harish and Cooper-White, Justin J. (2013) Microbioreactor array screening of Wnt modulators and microenvironmental factors in osteogenic differentiation of Mesenchymal progenitor cells. PLoS One, 8 12: e82931.1-e82931.15.

    Gelation Kinetics and Viscoelastic Properties of Pluronic and alpha-Cyclodextrin-Based Pseudopolyrotaxane Hydrogels
    Pradal, Clementine, Jack, Kevin S., Grondahl, Lisbeth and Cooper-White, Justin J. (2013) Gelation Kinetics and Viscoelastic Properties of Pluronic and alpha-Cyclodextrin-Based Pseudopolyrotaxane Hydrogels. Biomacromolecules, 14 10: 3780-3792.

    Full factorial screening of human embryonic stem cell maintenance with multiplexed microbioreactor arrays
    Titmarsh, Drew M., Ovchinnikov, Dmitry A., Wolvetang, Ernst J. and Cooper-White, Justin J. (2013) Full factorial screening of human embryonic stem cell maintenance with multiplexed microbioreactor arrays. Biotechnology Journal, 8 7: 822-834.

    Tailorable cell culture platforms from enzymatically cross-linked multifunctional poly(ethylene glycol)-based hydrogels
    Menzies, Donna J., Cameron, Andrew, Munro, Trent, Wolvetang, Ernst, Grondahl, Lisbeth and Cooper-White, Justin J. (2013) Tailorable cell culture platforms from enzymatically cross-linked multifunctional poly(ethylene glycol)-based hydrogels. Biomacromolecules, 14 2: 413-423.

    Lateral spacing of adhesion peptides influences human mesenchymal stem cell behaviour
    Frith, Jessica E., Mills, Richard J. and Cooper-White, Justin J. (2012) Lateral spacing of adhesion peptides influences human mesenchymal stem cell behaviour. Journal of Cell Science, 125 2: 317-327.

    Cameron AR, Frith JE, Cooper-White JJ. (2011) The influence of substrate creep on mesenchymal stem cell behaviour and phenotype. Biomaterials 32(26), 5979-5993.

    Hudson JE, Brooke G, Blair C, Wolvetang EJ, Cooper-White JJ. (2011) Development of myocardial constructs using modulus-matched acrylated polypropylene glycol triol substrate and different nonmyocyte cell populations. Tissue Engineering - Part A 17(17-18), 2279-2289.

    Vaquette C, Cooper-White JJ. (2011) Increasing electrospun scaffold pore size with tailored collectors for improved cell penetration. Acta Biomaterialia 7(6) 2544-57.

    Tan GK, Dinnes DLM, Butler LN, Cooper-White JJ. (2010) Interactions between meniscal cells and a self-assembled biomimetic surface composed of hyaluronic acid, chitosan and meniscal extracellular matrix molecules. Biomaterials 31(23), 6104-6118.

    Chau L, Doran M, Cooper-White JJ. (2009) A novel multishear microdevice for studying cell mechanics. Lab Chip 9(13), 1897-1902.

    George PA, Donose BC, Cooper-White JJ. (2009) Self-assembling polystyrene-block-poly(ethylene oxide) copolymer surface coatings: Resistance to protein and cell adhesion. Biomaterials 30(13) 2449-2456.

    Rowlands AS, George PA, Cooper-White JJ. (2008) Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation. American Journal of Physiology Cell Physiology 295(4), C1037-1044.

  • Professor Peter Gray


    Telephone: +61 7 334 63899 Email: p.gray1@uq.edu.au


    BSc Chem Eng (Hons) Syd, PhD NSW, FTSE, FIEAust, FAICD.
    Group Leader

    Professor Peter Gray is a pioneer of biotechnology research and development in Australia. In 2003 he was appointed AIBN’s inaugural Director and has since overseen the institute’s growth to 450 people and an annual turnover of $40million. Before joining AIBN, he was Professor and Head of Biotechnology at UNSW.

    Professor Gray has held academic positions at University College London and the University of California, Berkeley. He has had commercial experience in the US, working for Eli Lilly and Co and the Cetus Corporation. His research collaborations include groups at Stanford University; the University of California, Berkeley; and the University of British Columbia, Vancouver.

    Professor Gray serves on several boards and government committees. He is on the board of Engineering Conferences International, New York, a group that runs global, multi-disciplinary engineering conferences, many of which have played key roles in developing emerging industry sectors. The conferences include cell culture engineering; vaccine technology; and scale-up and manufacturing of cell-based therapies. Professor Gray also serves on the board of Biopharmaceuticals Australia Pty Ltd, the company established to build a GMP grade biopharmaceuticals manufacturing facility in Brisbane, and has been heavily involved in negotiations that led to DSM Biologics becoming the facility’s operator.

    Professor Gray is a Fellow and Vice-President of the Australian Academy of Technological Sciences and Engineering and a Fellow of the Australian Institute of Company Directors. He has chaired, served on organising committees for, and given plenary and keynote addresses at many key international conferences. In 2006 he attracted to Sydney and chaired the International Biotechnology Symposium – the first time a conference in the four-yearly series was held in the southern hemisphere. Professor Gray is a founder and past president of the Australian Biotechnology Association (Ausbiotech).

    Professor Gray has graduated more than 60 PhD students from his research group, in fields including secondary metabolite bioprocesses; bioconversion of cellulosic substrates; mammalian cell expression of complex proteins; nanoparticles for drug delivery; and the development of stem-cell based bioprocesses . He has twice been listed by Engineers Australia among the top 100 most influential engineers in Australia, and in 2001 was awarded the Australian Government’s Centenary Medal.

    Key publications in the past five years

    Codamo J, Munro TP, Hughes BS, Song M, Gray PP. (2011) Enhanced CHO cell based transient gene expression with the Epi-CHO expression system. Molecular Biotechnology 48(2), 109-115.

    Prowse ABJ, Chong F, Gray PP, Munro TP. (2011) Stem cell integrins: Implications for ex-vivo culture and cellular therapies. Stem Cell Research 6(1), 1-12.

    Prowse ABJ, Doran MR, Cooper-White JJ, Chong F, Munro TR, Fitzpatrick J, Chung TL, Haylock DN, Gray PP, Wolvetang EJ. (2010) Long-term culture of human embryonic stem cells on recombinant vitronectin in ascorbate free media. Biomaterials 31(32), 8281-8288.

    Ladewig K, Niebert M, Xu ZP, Gray PP, Lu GQ. (2009): Efficient siRNA delivery to mammalian cells using layered double hydroxide nanoparticles. Biomaterials 31(7), 1821-1829.

    Pilbrough W, Munro TP, Gray PP. (2009) Intraclonal protein expression heterogeneity in recombinant CHO cells. PLoS ONE 4(12), e8432. doi:10.1371/journal.pone.0008432.

  • Professor Mark Kendall, above, and his research explained in a TEDGlobal talk and a Rolex video, below (click to view) (photo courtesy of Rolex/Proudfoot).
    ARC Future Fellow and Group Leader
    BE (Hons I) UQ, PhD UQ


    Telephone: +61 7 334 64203 Email: m.kendall@uq.edu.au

    Research: Targeting the skin for needle-free, minimally invasive vaccine delivery and diagnostics for disease

    Professor Mark Kendall is the inventor of the Nanopatch, a needle-free vaccine delivery device which is under rapid research and development to product through spin-out company Vaxxas. Professor Kendall is a 2012 Rolex Laureate, recognising pioneering efforts to expand knowledge and improve human life. He co-founded Vaxxas with $15million in capital investment - one of the largest investments in an Australian start-up
    biotechnology company. The Nanopatch technology has been licensed to US-based pharma-
    ceutical company Merck & Co. Professor Kendall’s research group received the Eureka Prize for Research by an Interdisciplinary Team in 2011. Professor Kendall is an inaugural Australian Research Council Future Fellow.

    International links

    Professor Kendall has key international links spanning academia and industry including the University of Oxford, where he was a lecturer; Harvard; PATH; WHO; and the University of Washington. Professor Kendall is a member of a Scientific Advisory Group sponsored by the WHO that aims to fast−track the development of needle−free vaccine delivery technology for use in poor countries. His Nanopatch technology has been licensed to US –based pharmaceutical company Merck & Co. Professor Kendall has lectured at the University of Oxford. While there, he was instrumental in building up PowderJect/PowderMed, which was sold to Pfizer for $US400

    Memberships, patents and funding

    Professor Kendall is the recipient of more than $40 million in competitive research funding and another $33 million from industry. He edits papers in the Journal of Nanotechnology and Shock Waves Journal. Professor Kendall is the inventor of 96 patents.

    Awards and plenaries

    Professor Kendall is a Rolex Laureate, recognising pioneering efforts to expand knowledge and improve human life. He is the recipient of many prestigious accolades, including The Australian Innovation Challenge in 2011. His AIBN group received the 2011 Eureka Prize for Interdisciplinary Research; and the Queensland Clinical Trial Network and Merck’s 2010 Translational Research Excellence Commercialisation Award. Professor Kendall won the Australian Society for Medical Research and Amgen’s Australia Medical Researcher Award in 2008; and was named Young Engineer of Britain 2004. He has presented at more than 90 international seminars and conferences, including the plenary at the 9th Symposium of the Lohmann Therapie-Systeme Academy (LTS) in Germany in 2012.

    Key publications in the past five years

    Yeow B, Coffey JW, Muller DA, Grøndahl L, Kendall MAF, Corrie SR. (2013) Surface modification and characterization of polycarbonate microdevices for capture of circulating biomarkers, both in vitro and in vivo. Analytical Chemistry 85(21), 10196-10204.
    Coffey JW, Corrie SR, Kendall MAF. (2013) Early circulating biomarker detection using a wearable microprojection array skin patch. Biomaterials 34(37), 9572-9583.
    Pearson F, McNeilly CL, Crichton ML, Primiero CA, Yukiko SR, Fernando GJP, Chen X, Gilbert SC, Hill AVS, Kendall MAF. (2013) Dry-coated live viral vector vaccines delivered by Nanopatch microprojectsion retain long-term thermostability and induce transgene-specific T cell responses in mice. PLoS One 8(7), e67888.
    Meliga SC, Flaim C, Veidt M, Kendall MAF. (2013) The mechanical stress caused by micro-projection arrays penetrating the skin for vaccine delivery. Australian Journal of Multi-Disciplinary Engineering 10(2), 173-184.
    Raphael AP, Meliga SC, Chen X, Fernando GJP, Flaim C, Kendall MAF. (2013) Depth-resolved characterization of diffusion properties within and across minimally-perturbed skin layers. The Journal of Controlled Release 166(2), 87-94.
    Crichton ML, Chen X, Huang H, Kendall MAF. (2013) Elastic modulus and viscoelastic properties of full thickness skin characterised at micro scales. Biomaterials 34(8), 2087-2097.
    Fernando GJP, Chen X, Primero CA, Yukiko SR, Fairmaid EJ, Corbett HJ, Frazer IH, Brown LE, Kendall MAF. (2012) Nanopatch targeted delivery of both antigen and adjuvant to skin synergistically drives enhanced antibody responses. Journal of Controlled Release 159(2), 215-221.
    Crichton ML, Donose BC, Chen X, Raphael A, Huang H, Kendall MAF. (2011) The viscoelastic, hyperelastic and scale dependent behaviour of freshly excised individual skin layers. Biomaterials 32(20), 4670-4681.
    Chen X, Fernando GJP, Crichton ML, Flaim C, Yukiko SR, Fairmaid EJ, Corbett HJ, Primiero CA, Ansaldo AB, Frazer IH, Brown LE, Kendall MAF. (2011) Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization. Journal of Controlled Release 152(3), 349-355.
    Corrie S, Fernando GJP, Crichton ML, Brunck MEG, Anderson CP, Kendall MAF. (2010) Surface-modified microprojection arrays for intradermal biomarker capture, with low non- specific protein binding. Lab on a Chip 10, 2655-2658.
    Fernando GJP, Chen X, Prow TW, Crichton ML, Fairmaid EJ, Roberts MS, Frazer IH, Brown LE, Kendall MAF. (2010) Potent Immunity to Low Doses of Influenza Vaccine by Probabilistic Guided Micro-Targeted Skin Delivery in a Mouse Model. PLoS ONE 5(4), e10266. doi:10.1371/journal.pone.0010266.


  • Professor Stephen Mahler

    BSc (Hons) Syd, PhD UQ
    Affiliate Group Leader


    Telephone: +61 7 3365 4172 or +61 7 3346 3175 Email: s.mahler@eng.uq.edu.au

    Research: Research and development of biologic medicines

    Professor Stephen Mahler has made significant contributions to biopharmaceutical research and development and has been associated with translational research outcomes including development of monoclonal antibody biologics and antibody-targeted nanomedicines. He has secured more than $15 million in competitive research grants and industry funding during the past four years for projects principally associated with biologics discovery, recombinant protein production and development of targeted drug delivery systems. Professor Mahler has a track record of engagement with industry and is Director of the ARC Training Centre for Biopharmaceutical Innovation, partnering with CSL Ltd, the Australian Red Cross Blood Service, Patheon Biologics and GE Healthcare. He has collaborations with and consults for a wide range of biotechnology companies and industry stake holders both nationally and internationally.

    International links

    Professor Mahler has delivered short courses in biologics nationally and internationally to big pharma, biotechnology companies, regulatory agencies and universities, including Pfizer Australia; the National Pharmaceutical Control Bureau, Malaysia; and at the National Forum for Biosimilars, Brazil. He has consulted for a wide range of biotechnology companies both nationally and internationally including Pfizer and Abbott. He also has academic collaborations with University of Cambridge United Kingdom and Nanyang Technological University, Singapore in the areas of Antibody Engineering and Targeted Drug Delivery, respectively.

    Memberships, patents and funding

    Professor Mahler has been a member of the editorial board of the Journal of Chemical Technology and Biotechnology since 2004; and an OzReader for the Australian Research Council since 2003, reviewing ARC Discovery, Linkage, Australian Federation Fellowship, Australian Future Fellowships and ARC Centre applications. Prior to joining the AIBN, Professor Mahler was co-director of the Bioengineering Centre at the University of NSW, and secured $2 million in National Collaborative Research Infrastructure Strategy (NCRIS) funding for establishing the Recombinant Products NCRIS node at UNSW. Since 2007, Professor Mahler has been interacting with biotechnology companies and has secured research funding from industry sources. Two provisional patent applications are now in the process of being submitted.

    Awards and plenaries

    • Molecular medicine conference Asia, May 2013 (Click here for details)
    • Biopharma Asia Conference, March 2013 (Click here for details)

    Key publications for past five years

    Taylor K, Howard CB, Jones ML, Sedliarou I, MacDiarmid J, Brahmbhatt H, Munro TP and Mahler SM. (2015) Nanocell targeting using engineered bispecific antibodies. mAbs. 7, 53-65.

    Goodall SF, Howard CB, Jones ML, Trent Munro TP, Zhongfan Zhi Z, Montiero M and Mahler SM. (2014) An EGFR targeting immunomicelle nanoparticle self-assembled with a thermoresponsive polymer. J. Chem. Technol. and Biotechnol. DOI: 10.1002/jctb.4509.

    Leow H, Jones MJ, Cheng Q, Mahler SM and McCarthy J (2014) Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein II Malaria Journal 13, 277-287.

    Goodall SF, Jones ML and Mahler SM. (2014) Monoclonal antibody-targeted polymeric nanoparticles for cancer therapy – future prospects. J. Chem. Technol. and Biotechnol. DOI 10.1002/jctb.4555

    Munro TP, Mahler SM, Huang EP, Chin DY and Gray PP (2012) Bridging the gap: development of preclinical mAb candidates.Mabs 3, 440-452.

    Pile KD, Graham GG, Mahler SM, Day RO. (2011) Disease-modifying antirheumatic drugs. In Principles of immunopharmacology (third ed.). Nijkamp FP, Parnham MJ (Eds.), (pp. 585-619) Basel, Switzerland: Springer.

    Munro TP, Mahler SM, Huang EP, Chin DY, Gray PP. (2011) Bridging the gap: Facilities and technologies for development of early stage therapeutic mAb candidates. mAbs 3(5), 440-452.

    Falconer RJ, Jackson-Matthews D, Mahler SM. (2011) Analytical strategies for assessing comparability of biosimilars. J Chem Technol and Biotechnol 86(7), 915-922.

  • Professor Darren Martin

    BApplSci (Materials) UTS, PhD UTS
    AIBN Deputy Director (Graduate Studies) and Group Leader


    Telephone: +61 7 334 63870 Email: darren.martin@uq.edu.au

    Research: Renewable nanomaterials and Polymer nanocomposites

    Professor Darren Martin is a global leader in research and commercialisation of polyurethanes, polymer nanocomposites and renewable nanomaterials. In addition to many high impact publications, his research has led to several licensed and granted patents, with a proven track record in “end-to-end innovation”. The Martin Group takes fundamental discoveries and learnings in materials science and biology and progresses the science, engineering, regulation and translation of these technologies for the benefit of Queensland and Australia. Current active platforms include the unique cellulose nanofibres from Australian spinifex arid grasses, and organosilicate nano additives being commercialised by the AIBN spin-out company TenasiTech Pty Ltd.

    He has been an active researcher in both the ARC Centre of Excellence for Functional Nanomaterials and UQ’s Centre for High Performance Polymers. Martin has been the Founder and Chief Scientific Officer (CSO) of the successful UQ startup company TenasiTech Pty Ltd (www.tenasitech.com) since 2007. TenasiTech is the first Queensland start-up to receive Commercialisation Australia funding; has won the prestigious iLab Prize in the national Enterprize Competition; and received the 2010 UQ EAIT Commercialisation award.

    As inventor and research leader of the spinifex nanocellulose platform technology, Professor Martin won a 2016 UQ Partners in Research Excellence Award (PIREA) for ongoing engagement, co-development and commercialisation of this technology with The Dugalunji Aboriginal Corporation in remote NW QLD.


    Professor Martin’s local and international collaborators include Monash University, The University of Auckland, The University of Padova, Italy, Purdue University, USA, and several others in North America, Europe and Asia.

    In 2016 Professor Martin was involved in signing an agreement between UQ and the Dugalunji Aboriginal Corporation (DAC) to recognise local Aboriginal traditional owners’ knowledge about spinifex and to ensure that they will have ongoing equity and involvement in the commercialisation of the nanocellulose technology. His team currently work with DAC and several local and international organisations and companies to co-develop, trial and translate this renewable nanotechnology platform.

    Memberships, patents and funding

    Professor Martin has been the recipient of three Australian Research Council (ARC) Discovery Grants and has secured more than $12.5 million in research and commercialisation funding since 1999. He has worked with Australian regulators such as NICNAS and WorkSafe Australia on policy for nanomaterials/nanocomposites safety and occupational hygiene. Professor Martin has been an active member of the Engineers Australia Nanoengineering panel and has presented more than 15 keynotes and plenary talks to international conferences, and in recent times has often been asked to provide perspective on discovery, innovation and translation. During the past five years a large proportion of his research funding has been derived from the private sector.

    Professor Martin is an inventor on the following list of patent families in the fields of polymer nanocomposites and nanocellulose:

    • Granted Patent - D.J. Martin and G.A. Edwards, The University of Queensland, “Polymer Composite” – Priority Aug 30, 2004, PCT May 19, 2005 (WO/2006/024068), First Granted 9 Dec 2010 (AU, CAN, USA)
    • Granted Patent - D.J. Martin and G.A. Edwards, The University of Queensland, “Polymer Composites Having Particles With Mixed Organic Modifications” – Priority Apr 15, 2008, PCT Apr 15, 2009 (WO/2009/127000), First Granted 21 Jan 2014 (USA, EU, AU)
    • Granted Patent - D.J. Martin, G.A. Edwards and C. Chaleat, The University of Queensland, “Scratch resistant polymers” – Priority Jun 6, 2013, PCT Jun 5, 2014 (WO/2014/194380) (AU, BRA, CHN, IND, USA, EU)
    • PCT Patent - D.J. Martin, N. Amiralian and P. A. Kumar, The University of Queensland, “Nanocellulose” – Priority Nov 22, 2013, PCT Nov 21, 2014 (WO/2015/074120)
    • PCT Patent - D.J. Martin and N. Amiralian, The University of Queensland, “Nanocomposite Elastomers” – Priority 8 Dec, 2014, PCT 7 Dec, 2015 (PCT/AU2015/050773)

    Key publications

    Belcher C, Marshall R, Edwards G, Martin DJ. (2012) The Commercialization of Nanotechnology: The Five Critical Success Factors to a Nanotech-enabled Whole Product, in Nanotechnology Commercialization. Tsuzuki T (Ed.), Singapore: Pan Stanford Publishing. ISBN: 9789814303286.

    Amiralian, N., Annamalai, P. K., Memmott, P., Taran, E., Schmidt, S. and Martin, D. J. (2015), Easily deconstructed, high aspect ratio cellulose nanofibres from Triodia pungens; an abundant grass of Australia's arid zone. RSC Advances, 5(41), 32124-32132.

    Amiralian, N., Annamalai, P. K., Memmott, P. and Martin, D. J. (2015), Isolation of cellulose nanofibrils from Triodia pungens via different mechanical methods. Cellulose, 22(4), 2483-2498.

    Mortimer G. M., Butcher N. J., Musumeci A. W., Deng Z. J., Martin D. J. and Minchin R. F. (2014), Cryptic epitopes of albumin determine mononuclear phagocyte system clearance of nanomaterials. ACS Nano, 8(4), 3357-3366.

    Andriani, Y., Jack, K. S., Gilbert, E. P., Edwards, G. A., Schiller, T. L., Strounina, E., Osman, A.F. and Martin, D. J. (2013). Organization of mixed dimethyldioctadecylammonium and choline modifiers on the surface of synthetic hectorite. Journal of Colloid and Interface Science, 409, 72-79.

    Musumeci, A., Gosztola, D., Schiller, T., Dimitrijevic, N. A., Vladimiro, M., Martin D. and Rajh, T. (2009). SERS of semiconducting nanoparticles (TiO2 hybrid composites). JACS Communication, 131(17), 6040-6041.

    McNally, T., Pötschke, P., Halley, P., Murphy, M., Martin, D., Bell, S. E. J., Brennan, G. P., Bein, D., Lemoine, P. and Quinn, J. P. (2005). Polyethylene multiwalled carbon nanotube composites. Polymer, 46(19), 8222-8232.

    Smart, S. K., Cassady, A. I., Lu, G. Q. and Martin, D. J. (2006). The biocompatibility of carbon nanotubes. Carbon, 44(6), 1034-1047.

    Finnigan, B., Jack, K., Campbell, K., Halley, P., Truss, R., Casey, P., Cookson, D., King, S. and Martin, D. (2005). Segmented polyurethane nanocomposites: Impact of controlled size nanofillers on the morphological response to uniaxial deformation. Macromolecules, 38(17), 7386-7396.

    Finnigan, B., Martin, D., Halley, P., Truss, R. and Campbell, K. (2004). Morphology and properties of thermoplastic polyurethane nanocomposites incorporating hydrophilic layered silicates. Polymer, 45(7), 2249-2260.

    Martin, D. J., Poole-Warren, L. A., Gunatillake, P. A., McCarthy, S. J., Meijs, G. J. and Schindhelm, K. (2000). Polydimethylsiloxane/polyether-mixed macrodiol-based polyurethane elastomers: biostability. Biomaterials, 21(10), 1021-1029.

    Recent publications

    Full list of publications available at UQ eSpace.

  • Professor Michael Monteiro
    BSc (Hons) Griffith, PhD Griffith
    ARC Future Fellow and Group Leader


    Telephone: +61 7 334 64164 Email: m.monteiro@uq.edu.au

    Research: Designer polymers: Synthesis of complex polymer architectures

    Professor Michael Monteiro has established an international reputation in the field of 'living' radical polymerization to create complex polymer architectures. He is now building designer polymers for various biomedical applications, including vaccines, drug delivery and stem cells. He is dedicated to translating research into commercial outcomes, with 7 PCT and provisional patents since 2005 and start-up company DendriMed Pty Ltd. He was awarded an ARC QEII Fellowship in 2004 and an ARC Future Fellowship in 2009. He has attracted ARC and NHMRC grants; and Queensland State Government funding in excess of $7 million.

    International links

    Professor Monteiro has built a strong collaboration with Professor Virgil Percec from the University of Pennsylvania to develop and understand the new SET-LRP. He has developed a collaboration with Professor Rachel O'Reilly from the University of Warwick to develop nanoreactors that mimic enzyme activity. In collaboration with Professor Eugenia Kumacheva from the University of Toronto, they developed temperature responsive micron-sized particles from encapsulation of cells.

    Memberships, funding and patents

    • Editorial Advisory Boards: Biomacromolecules (ACS Journal) (2013- ), Macromolecules (ACS Journal) (2008-2010), Journal of Polymer Science Part A Polymer Chemistry (2009-)
    • ARC Funding: DP120100973 Prof MJ Monteiro; Dr TP Munro, On-demand scaffolds for directed stem cell differentiation
    • Selected Patents: (i) Release Media Prov. AU2012902396, (ii) Polymeric dendrimers for siRNA delivery Prov. AU2012903138

    Awards and plenaries

    2013 UNESCO, Stellenbosch, SA Plenary
    2013 ACS, New Orleans., USA – Invited lecture
    2013 IPCG, Shanghi, China, Invited and Co-chair
    2012 Australian Polymer Symposium, Hobart, Keynote
    2012 IUAPC POC14, Qatar, Keynote
    2011 Australian Leadership Award (ADC)

    Key publications for the past five years

    Jia ZF, Lonsdale DE, Kulis J, Monteiro MJ. (2012) Construction of a 3-Miktoarm Star from Cyclic Polymers. Acs Macro Letters 1(6), 780-783.

    Kessel S, Urbani CN, Monteiro MJ. (2011) Mechanically Driven Reorganization of Thermoresponsive Diblock Copolymer Assemblies in Water. Angew Chemie - Int Ed 50(35), 8082-8085.

    Deng ZJ, Liang MT, Monteiro MJ, Toth I, Minchin RF. (2011) Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nature Nanotechnology 6(1), 39-44.

    Bell CA, Bernhardt PV, Monteiro MJ. (2011) A Rapid Electrochemical Method for Determining Rate Coefficients for Copper-Catalyzed Polymerizations. J Am Chem Soc 133(31), 11944-11947.

    Skwarczynski M, Zaman M, Urbani CN, Lin IC, Jia Z, Batzloff MR, Good MF, Monteiro MJ, Toth I. (2010) Polyacrylate dendrimer nanoparticles: a self-adjuvanting vaccine delivery system. Angew Chem Int Ed 49(33), 5742-5745.

    Kulis J, Bell CA, Micallef AS, Jia Z, Monteiro MJ. (2009) Rapid, Selective, and Reversible Nitroxide Radical Coupling (NRC) Reactions at Ambient Temperature. Macromolecules 42(21), 8218-8227.

  • Professor Lars Nielsen

    Cand Polyt Denmark, PhD UQ
    Group Leader


    Telephone: +61 7 334 63986+61 7 334 63986 Email: lars.nielsen@uq.edu.au

    Research: Systems and synthetic biology

    Professor Lars Nielsen is leading the development of experimental and computational tools to analyse and design complex biological systems. His expertise in metabolic modelling and flux analysis is available nowhere else in Australia – and in few labs across the world. Professor Nielsen’s studies of biological systems as diverse as bacteria, baker's yeast, sugarcane, insects and mammals has attracted industrial partnerships with companies including Dow, Metabolix, Amyris, LanzaTech, Boeing, Virgin Australia and GE. These metabolic engineering partnerships have focussed on developing new ways of producing aviation fuel, various materials and bioactives (antibiotics, biopesticides, monoclonal antibodies). Professor Nielsen is also applying system analysis and design approaches to tissue engineering including novel strategies for generating microtissues for drug screening and using stem cells to produce red and white blood cells for transfusion.

    International links

    Professor Nielsen collaborates with some of the world’s pre-eminent metabolic engineers. A joint project with Prof Sang Yup Lee (KAIST, Korea) enabled several extended mutual visits to explore use of sugar for higher value products. A separate project focused on producing synthetic aviation fuel based on isoprenoids involves Professor Nielsen collaborating with global synthetic biotechnology company Amyris and leading isoprenoid metabolic engineer Professor Jay Keasling, from UC Berkeley. Professor Nielsen has secured $8million since 2006 from industry through research grants with US, European, Japanese, Korean, New Zealand and Australian companies.

    Memberships, patents and funding

    Professor Nielsen has been granted four patents – two in stem cells and another two in metabolic engineering. He is on the Scientific Advisory Board of InSphero (2009–), a Swiss company commercialising microtissue technology originating in the Nielsen laboratory. He is an editorial board member of ACS Synthetic Biology, Metabolic Engineering, Biotechnology Journal, Biotechnology and Bioengineering and Bioprocess and Biosystems Engineering. Professor Nielsen formed and chaired the 2005 CRC SIIB Industrial Biotechnology Panel to develop an industrial biotechnology strategy for the Australian sugar industry. He successfully lobbied for the inclusion of Industrial Biotechnology in the Queensland Biotechnology Strategic Plan 2005-2015. Since then he has served as expert advisor to government, research bodies, domestic and major international companies such as Dow Chemical, DuPont and GS Caltex. In the past decade, he has been part of successful research grant applications totalling $56 million, with $31.2 million for his own systems and synthetic biology group at AIBN.

    Awards and plenaries

    Professor Nielsen has received the UQ Foundation Research Excellence Award; and the Australian Institute of Political Science Queensland Young Tall Poppy Award. He was invited to speak at the 2010 Science at the Shine Dome Symposium on Genomics & Mathematics, Canberra; and the Australian Academy of Technical Sciences & Engineering’s National Symposium on Future-Proofing Australia.

    Key publications

    Licona-Cassani C, Lim SA, Marcellin E, Nielsen LK (2014) Temporal dynamics of the Saccharopolyspora erythraea phosphoproteome. Molecular and Cellular Proteomics 13:1219-30. No citations. Funded through consulting.

    de Oliveira Dal'molin CG, Quek LE, Palfreyman RW, Brumbley SM, Nielsen LK. (2010) AraGEM - a Genome-Scale Reconstruction of the Primary Metabolic Network in Arabidopsis thaliana. Plant Physiol 152, 579–589.

    Quek L-E, Dietmair S, Krömer JO, Nielsen LK. (2010) Metabolic flux analysis in mammalian cell culture. Metabolic Engineering 12, 161-171.

    Timmins NE, Palfreyman E, Marturana F, Dietmair S, Luikenga S, Lopez G, Fung YL, Minchinton R, Nielsen LK. (2009) Clinical Scale Ex vivo Manufacture of Neutrophils from Hematopoietic Progenitor Cells. Biotechnol Bioeng 104, 832-840.

    Chen W, Marcellin E, Hung J, Nielsen LK. (2009) Hyaluronan molecular weight is controlled by UDP-N- acetylglucosamine concentration in Streptococcus zooepidemicus. J Biol Chem 284, 18007-18014.

    Recent publications

    Full list of publications available at UQ eSpace.

  • Professor Matt Trau and, below, videos relevant to his research. The first video is Prof Matt Trau in conversation with Dr Leroy Hood & Ravinder Sajwan recorded at the Consilium 2015 Conference (Sanctuary Cove, Aug 2015) as part of a session entitled “The new Science of Ageing and Wellness”. The second was recorded by the National Breast Cancer Foundation.

    BSc (Hons) Syd, PhD (Physical Chemistry) Melb
    AIBN Deputy Director and Group Leader

    Centre for Personalised NanoMedicine

    The Trau Laboratory website


    Telephone: +61 7 334 64173 Email: m.trau@uq.edu.au

    Research: Nanoscience, Nanotechnology, Molecular diagnostics

    Professor Matt Trau is currently a Professor of Chemistry at The University of Queensland; and is also Deputy Director and co-founder of the Australian Institute for Bioengineering and Nanotechnology. Since graduating from the University of Sydney (BSc Hons I, University Medal) and the University of Melbourne (PhD in Physical Chemistry, 1993), he has held positions in industry and academia across the globe. These include a Fulbright Research Fellowship at Princeton University, USA; and a research
    scientist at Dow Chemical and ICI Pty Ltd. Professor Trau has been a Visiting Professor at two of the largest Cancer Research Centres in the world: The Dana Farber Cancer Research Institute, Harvard Medical School, Boston (2000); and the Fred Hutchinson Cancer Research Centre, Seattle (2008). Professor Trau is internationally recognised for his innovative and cross-disciplinary research at the interface between chemistry, nanotechnology, biology and medicine. He has co-authored more than 120 refereed publications, many of which appear in the highest impact journals in his field, e.g., two Nature and two Science publications. His major awards and honours include an ARC Federation Fellowship (one of the most prestigious scientific fellowships in Australia), a Fulbright Research Fellowship to the USA; a Queensland Young Tall Poppy Award; a UQ Foundation/Vice Chancellor’s Research Excellence Award; a Paul Harris Fellowship; and a Pink Circle Award for breast cancer research excellence.

    Leadership of major multi-disciplinary international programs

    Professor Trau has raised more than $22 million in competitive national and international grant funding in the past 10 years. In the last five years, Professor Trau has initiated and led
    several large international programs that involve close collaboration between leading nanotechnologists, molecular biologists, geneticists and commercial researchers - with the
    goal of creating cutting edge diagnostics. These include a $4 million National and International Research Alliances Program (NIRAP) grant from the Queensland government ("International Partnership for preventative and Personalised Medicine)"; and two consecutive $5 million multidisciplinary collaborative grants from the National Breast Cancer Foundation (NBCF):
    "Novel strategies for Prediction and Control of Advanced Breast Cancer via Nanoscaled Epigenetic-Based Biosensors", 2008-2013; and "Enabling Clinical Epigenetic Diagnostics: The Next Generation of Personalized Breast Cancer Care", 2013-2018. These grants involve research collaborations with some of the highest calibre scientists in the world, e.g., Dr Lee Hartwell (2001 Nobel Laureate) from Seattle was a co-chief investigator on the NIRAP grant, and each of the NBCF grants include leading geneticists, pathologists and oncologists from across Australia and around the world. In the past five years, he has been a consultant for a range of national and international companies such as Merck, Digene, Beckman Coulter, Panbio and A.I. Scientific, as well as being the founder and Director of Nanomics BioSystems Pty Ltd (a spinoff company from his laboratory).

    Major plenary lectures and international conferences

    Since 2003, Professor Trau has presented more than 60 invited plenary/keynote lectures at major international conferences spanning the disciplines of Chemistry, Nanotechnology, Chemical Engineering, Cancer and Diagnostics. Recent examples include: the 4th International NanoBio Conference, (Seattle) 2012; the 14th International Colloid & Surface Science Conference, (Japan) 2012; "Cancer Nanotechnology" Gordon Research Conference, (USA) 2011; the WA Cancer Conference 2011; Sydney Cancer Conference, 2010. In the past 10 years, Professor Trau has played the role of conference convenor, chair, co-chair and symposium chair for 10 major international conferences. Recent examples include: immediate past chair of the 1st International Conference on BioNano Innovation, (Brisbane) 2012; co-chair of the 5th International NanoBio Conference scheduled for Brisbane in 2014. 

    Make a difference to Professor Trau's research by donating today.

    (please select "Other" under "Make a gift to" and enter Professor Trau's name)


    Recent Media

    "Single Drop Genomics" UQ media release. March 2015

    Recent Publications

    Reviews & Commentaries

    Wee, E. J. H.; Trau, M., Enzyme catalysis: Evolution made easy, Nature Chemistry, 6, 756-757, 2014.

    Refereed Journal Articles 

    Wong, N.C.L; Pope, B.J; Candiloro, I; Korbie, D; Trau, M; Wong, S.Q; Mikeska, T; van Denderen, B.J; Thompson, E.W; Eggers, S; Doyle, S; Dobrovic, A. Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat. GigaScience, 2015, Accepted November 2015.

    Vaidyanathan, R; Dey, S; Carrascosa, L. G.; Shiddiky, M. J. A.; Trau, M. AC Electrohydrodynamics at the Nanoscale: Pushing Biomolecules and Cells around on Surfaces. Biomicrofluidics, 2015, Accepted November 2015. 

    Vaidyanathan, R; Rauf, S; Grewal, Y; Spadafora, L; Shiddiky, M. J. A; Cangelosi, G; Trau, M. Enhancing Protein Capture Using a Combination of Nanoyeast Single-Chain Fragment Affinity Reagents and Alternating Current Electrohydrodynamic Forces. Anal. Chem., 2015, Accepted November 2015.

    Ng, B. Y. C; Wee, E. J. H.; West, N. P.; Trau, M. Rapid DNA detection of Mycobacterium tuberculosis - towards single cell sensitivity in point-of-care diagnosis. Sci. Rep., 2015, 5, 15027. doi:10.1038/srep15027.

    Wee, E. J. H.; Ngo, T. H.; Trau, M. A simple bridging flocculation assay for rapid, sensitive and stringent detection of gene specific DNA methylation. Sci. Rep., 2015, 5, 15028.

    Ng, B. Y. C; Xiao, W; West, N; Wee, E. J. H; Wang, Y; Trau, M. Rapid, Single-Cell Electrochemical Detection of Mycobacterium tuberculosis Using Colloidal Gold Nanoparticles. Anal. Chem., 2015, 87, 20, 10613-10618

    Stone, A.; Zotenko, E.; Locke, W.; Korbie, D.; Millar, E.; Pidsley, R.; Stirzaker, C.; Graham, P.; Trau, M.; Musgrove, E.; Nicholson, R.; Gee' J.; Clark, S. DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer. Nat. Commun., 2015, 6, 7758.

    Wee, E. J. H.; Ngo, T. H.; Trau, M. Colorimetric detection of both total genomic and loci-specific DNA methylation from limited DNA inputs. Clin. Epigenet., 2015, 7, 1, 1-9.

    Koo, K. M.; Sina, A. A. I.; Carrascosa, L. G.; Shiddiky, M. J. A.; Trau, M. DNA-Bare Gold Affinity Interactions: Mechanism and Applications in Biosensing. Anal. Methods, 2015, 7, 7042 - 7054.

    Wang, Y.; Wee, Eugene J.H.; Trau, M. Highly sensitive DNA methylation analysis at CpG resolution by surface-enhanced Raman scattering via ligase chain reaction. Chem. Commun., 2015, 51, 10953 - 10956.

    Wang, Y.; Vaidyanathan, R.; Muhammad J. A. S.; Trau, M. Enabling Rapid and Specific Surface Enhanced Raman Scattering Immunoassay Using Nano-Scaled Surface Shear Forces. ACS Nano, 2015, 9, 6, 6354–6362.

    Grewal, Y. S., Shiddiky, M. J. A., Spadafora, L. J., Cangelosi, G. A. & Trau, M. Structural Characterization of Nanoyeast Single-Chain Fragment Variable Affinity Reagents. J. Phys. Chem. C, 2015. 119, 22, 12674-12680.

    Vaidyanathan, Ramanathan, van Leeuwen, Lara Michelle, Rauf, Sakandar, Shiddiky, Muhammad J. A. and Trau, Matt. A multiplexed device based on tunable nanoshearing for specific detection of multiple protein biomarkers in serum. Scientific Reports, 2015 5 9756. 

    Wee, Eugene JH, Sakandar Rauf, Muhammad JA Shiddiky, Alexander Dobrovic, and Matt Trau. DNA ligase-based strategy for quantifying heterogeneous DNA methylation without sequencing. Clinical chemistry, 2015, 61, 1, 163-171. 

    Korbie, Darren, Lin, Erica, Wall, David, Nair, Shalima S., Stirzaker, Clare, Clark, Sue J. and Trau, Matt. Multiplex bisulfite PCR resequencing of clinical FFPE DNA. Clin. Epigenet., 2015, 7, 28, 1-11.

    O'Leary, V. B.; Ovsepian, S. V.; Carrascosa, L. G.; Buske, F. A.; Radulovic, V.; Niyazi, M.; Moertl, S.; Trau , M.; Anastasov, N.; Atkinson M. J.  PARTICLE – a triplex-forming long noncoding RNA amends locus specific methylation in response to low dose irradiation. Cell Rep., 2015, 11, 3, 474-485. 

    Wee, E. J. H., Lau, H. Y., Botella, J. R. and Trau, M. Re-purposing bridging flocculation for onsite, rapid, qualitative DNA detection in resource-poor settings, Chem. Commun. 2015, 51, 5828-5831. (Front Cover)

    Stirzaker, C., Zotenko, E., Song, J., Qu, W., Nair, S., Locke, W., Stone, A., Armstong, N., Robinson, M., Dobrovic, A., Avery-Kiejda, K., Peters, K., French, J., Stein, S., Korbie, D., Trau, M., Forbes, J., Scott, R., Brown, M., Francis, G., Clark, S. Methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value, Nature Communications, 2015, Feb 2. doi: 10.1038/ncomms6899. 

    Lane, R., Korbie, D., Anderson,W., Vaidyanathan, R. and Trau, M. Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing, Scientific Reports, 2015. 5, 7639.1-7639.7.

    Wee, E. J. H.; Trau, M., Measuring whole genome methylation via oxygen channelling chemistry, Chemical Communications, 50, 74, 10894-10896, 2014.

    Wee, E. J. H.; Rauf, S.; Shiddiky, M. J.; Dobrovic, A.; Trau, M., DNA ligase-based strategy for quantifying heterogeneous DNA methylation without sequencing, Clinical Chemistry, 61, 1, 2014.

    Wang, Y.; Rauf, S.; Grewal, Y. S.; Spadafora, L. J.; Shiddiky, M. J.; Cangelosi, G.; Schlücker, S.; Trau, M., Duplex microfluidic SERS detection of pathogen antigens with nanoyeast single-chain variable fragments, Analytical Chemistry, 86, 19, 9930-9938, 2014

    Vaidyanathan, R.; Shiddiky, M. J. A.; Rauf, S.; Dray, E.; Tay, Z.; Trau, M., Tunable “nano-shearing”: A physical mechanism to displace nonspecific cell adhesion during rare cell detection, Analytical Chemistry, 86, 4, 2042-2049, 2014.

    Vaidyanathan, R.; Rauf, S.; Shiddiky, M. J. A.; Trau, M., Tuneable surface shear forces to physically displace nonspecific molecules in protein biomarker detection, Biosensors and Bioelectronics, 61, 184-191, 2014.

    Vaidyanathan, R.; Rauf, S.; Dray, E.; Shiddiky, M. J. A.; Trau, M., Alternating current electrohydrodynamics induced nanoshearing and fluid micromixing for specific capture of cancer cells, Chemistry – A European Journal, 20, 13, 3724-3729, 2014.

    Sina, A. A. I.; Howell, S.; Carrascosa, L. G.; Rauf, S.; Shiddiky, M. J.; Trau, M., eMethylsorb: electrochemical quantification of DNA methylation at CpG resolution using DNA–gold affinity interactions, Chemical Communications, 50, 13153-13156, 2014.

    Sina, A. A. I.; Carrascosa, L. G.; Palanisamy, R.; Rauf, S.; Shiddiky, M. J.; Trau, M., Methylsorb: A simple method for quantifying DNA methylation using DNA-gold affinity interactions, Analytical Chemistry, 86, 20, 10179-10185, 2014.

    Shiddiky, M. J. A.; Vaidyanathan, R.; Rauf, S.; Tay, Z.; Trau, M., Molecular nanoshearing: An innovative approach to shear off molecules with AC-induced nanoscopic fluid flow, Scientific Reports, 4, 3716, 2014

    Shah, A. M.; Hill, M. M.; Shiddiky, M. J.; Trau, M., Electrochemical detection of glycan and protein epitopes of glycoprotein in serum, Analyst, 139, 22, 5970-5976, 2014.

    Rauf, S.; Shiddiky, M. J. A.; Trau, M., Electrohydrodynamic removal of non-specific colloidal adsorption at electrode interfaces, Chemical Communications, 50, 37, 4813-4815, 2014.

    Lau, H. Y.; Palanisamy, R.; Trau, M.; Botella, J. R., Molecular inversion probe: A new tool for highly specific detection of plant pathogens, PLOS ONE, 9, 10, e111182, 2014.

    Koo, K. M.; Wee, E. J. H.; Rauf, S.; Shiddiky, M. J. A.; Trau, M., Microdevices for detecting locus-specific DNA methylation at CpG resolution, Biosensors and Bioelectronics, 56, 278-285, 2014.

    Koo, K. M.; Sina, A. A. I.; Carrascosa, L. G.; Shiddiky, M. J.; Trau, M., eMethylsorb: Rapid quantification of DNA methylation in cancer cells on screen-printed gold electrodes, Analyst, 139, 23, 6178-6184, 2014

    Grewal, Y. S.; Shiddiky, M. J. A.; Spadafora, L. J.; Cangelosi, G. A.; Trau, M., Nano-yeast–scFv probes on screen-printed gold electrodes for detection of Entamoeba histolytica antigens in a biological matrix, Biosensors and Bioelectronics, 55, 417-422, 2014.

    Carrascosa, L. G.; Sina, A. A. I.; Palanisamy, R.; Sepulveda, B.; Otte, M. A.; Rauf, S.; Shiddiky, M. J. A.; Trau, M., Molecular inversion probe-based SPR biosensing for specific, label-free and real-time detection of regional DNA methylation, Chemical Communications, 50, 27, 3585-3588, 2014

    New book published by the Trau lab in 2013

    Shiddiky MJA, Wee EJH, Rauf S, Trau M (Eds). (2013) Microfluidics, Nanotechnology and Disease Biomarkers for Personalized Medicine Applications. New York, US. Nova Biomedical.

    Available in electronic and hardcopy from Nova Publishers, New York. Click here to view.

    Student Opportunities

    The Trau laboratory is interested in recruiting enthusiastic, high calibre students.

    Apply for an Honours project with us.

    Apply for a PhD or MPhil project with us.



  • Dr Claudia Vickers

    BSc (Hons I) UQ, PhD UQ/CSIRO
    AIBN Group Leader


    Telephone: +61 7 334 63958, Email: c.vickers@uq.edu.au

    RESEARCH: Synthetic biology to examine basic metabolic processes and build novel biological parts and devices

    A/Professor Vickers applies synthetic biology approaches to answering key fundamental biological questions and to development/improvement of industrial bio-processes. She is particularly interested in using biology to replace current industrial practices (largely based on finite petrochemical resources) with sustainable, environmentally friendly processes. To this end, she uses the tools of systems and synthetic biology for metabolic engineering of organisms. Metabolic engineering is the rational redesign of organisms for production of specific industrially-useful compounds. A/Professor Vickers’ research is focussed on a large group of natural products called isoprenoids. Isoprenoids have many different biological functions; they also have a multitude of biotechnological applications (including pharmaceuticals, flavours, fragrances, agricultural chemicals, and biofuels). The group works in yeast (Saccharomyces cerevisiae), Escherichia coli, cyanobacteria (Synechocystis and Synechococcus spp.), Pseudomonas putida, and plants (various species). The major aim of the research program is to understand metabolic regulation through the isoprenoid pathways and to engineer carbon flux for industrial production. The group has developed many enabling molecular biology/synthetic biology tools for both plants and microbes; these tools are used in hundreds of labs across the world.

    A/Professor Vickers obtained a BSc (Hons I) in molecular biology from the University of Queensland in 1998 and a PhD in plant molecular biology (cereal crop biotechnology) through CSIRO Plant Industry and The University of Queensland in 2004. She held a post-doctoral position at The University of Essex and Visiting Scientist position at the University of Lancaster 2004-2007, where she worked on abiotic stress and isoprene production in plants. She returned to The University of Queensland in 2007, joining the Australian Institute for Bioengineering and Nanotechnology to expand her research program into microbial metabolic engineering.

    A/Professor Vickers has worked with industry partners in a range of application areas to deliver industry-focused outcomes and provide consulting expertise. She has also acted as an advisor on synthetic biology and industrial biotechnology for the Australian Federal Government, the Queensland Government, and the Institute on Science for Global Policy.

    Since January 2017 A/Professor Vickers has held a joint appointment with CSIRO to lead their Synthetic Biology Future Science Platform (SynBio FSP).

    Industry Engagement and Collaborations

    The group has collaborated with industry on a variety of different projects. Partners include: Queensland Department of Agriculture Fisheries and Forestry (DAFF Q), PepsiCo (USA), Samyang Biopharmaceuticals Corporation (Korea), Sanitarium, Lion (the brewing company), the XXXX Brewery, Stone & Wood Brewery, Joe White Maltings (now owned by Cargill), CSR Ltd, GS Caltex, Boeing Australia, Mackay Sugar Ltd, IOR Energy, Virgin Australia, Lawrence Berkeley National Laboratories (USA), and Amyris (USA). Current academic collaborations include partners at The University of Queensland, CSIRO Land & Water, The University of Technology Sydney, Tianjin University (China), and Utsunomiya University (Japan).


    A/Professor Vickers has won numerous awards and Fellowships, including a Queensland Government Smart State Fellowship (2010), the University of Queensland Foundation Research Excellence Award (2013), a Queensland Government Accelerate Fellowship (2014), and a Young Tall Poppy Science Award (Australian Institute of Policy & Science; 2014). She has been working to develop and support synthetic biology across Australia and New Zealand for several years; as part of this initiative, she is founding President of Synthetic Biology Australasia (SBA).

    Key Publications

    Peng, B.Y.; Plan, M.; Chrysanthopoulos, P.; Hodson, M.; Nielsen, L.K.; Vickers, C.E.* (2016) A squalene synthase protein degradation method for improved sesquiterpene production in Saccharomyces cerevisiae. Metabolic Engineering 39:209-219

    Vickers, C.E.*; Bongers, M.; Qing, L.; Delatte, T.; Bouwmeester, H. (2014) Metabolic engineering of volatile isoprenoids in plants and microbes. Plant Cell & Environment 37(8):1753-1775

    Williams, T.C.; Nielsen, L.K.; Vickers, C.E.* (2013) Engineered quorum-sensing using pheromone-mediated cell-to-cell communication in Saccharomyces cerevisiae. ACS Synthetic Biology 2(3):136-149

    Vickers, C.E.*; Blank, L.M.; Kroemer, J.O. (2010) Chassis cells for industrial biochemical production. Nature Chemical Biology 6(12):875–877

    Vickers, C.E.*; Gershenzon, J.; Lerdau, M.; Loreto, F. (2009) A unified mechanism of action for volatile isoprenoids in plant abiotic stress. Nature Chemical Biology 5:283-291 (invited)

    Full list of publications available on UQ espace


    Strain Improvement and optimization studies for enhanced production of GGPP (Geranylgeranyl Pyrophosphate)
    (2016–2018) Samyang Biopharmaceuticals Corporation

    Beverage Mouthfeel Ingredient Exploration via Leveraging Brewing Science and Systems Biology

    (2015-2017) PepsiCo USAA sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    (2015) UQ Major Equipment and Infrastructure

    From sugarcane to bio-products via microbial cell factories: Making sustainable, environmentally friendly agriculture chemicals to enhance crop productivity
    (2014–2018) Queensland Government Accelerate Fellowships

    Toward sustainable diesel production using microbial cells: unravelling isoprenoid pathway regulation through systems biology
    (2014–2016) ARC Discovery Projects

    Investigating the important foam positive proteins from malt
    (2014–2015) UQ Collaboration and Industry Engagement Fund

    From a petrochemical economy to a biochemical economy: Using synthetic biology to produce sustainable, environmentally friendly fuels and chemicals from engineered microbial cell bio-factories
    (2014) UQ Foundation Research Excellence Awards - DVC(R) Funding

    Multichannel potentiostats to drive microbial and electrochemical production processes
    (2011) UQ Major Equipment and Infrastructure

    Queensland Sustainable Aviation Fuel Initiative
    (2010–2014) Queensland Government Smart State National and International Research Alliances Program

    Smart Futures Fellowship: Engineering sucrose-based industrial isoprenoid production in yeast cells
    (2010–2014) Queensland Government Smart Futures Fellowships


  • Professor Lianzhou Wang

    PhD, Shanghai Institute of Ceramics, Chinese Academy of Sciences, China
    ARC Future Fellow and Affiliate Group Leader


    Telephone: +61 7 334 54218 Email: l.wang@uq.edu.au

    Research: Characterisation and application of functional nanomaterials

    Professor Lianzhou Wang has an international reputation in the characterisation and application of functional nanomaterials for use in renewable energy conversion/storage systems, including photocatalysts, rechargeable lithium batteries, and new generation solar cells. Professor Wang is an Australian Research Council (ARC) Future Fellow; and past recipient of an STA Fellowship of Japan; and an ARC Queen Elizabeth II Fellowship. He has attracted more than 12 ARC grants; two CSIRO Flagship Cluster projects; major Queensland Government funding, an CRC program and a number of UQ grants.

    International links

    Professor Wang has built strong international links and nurtured long term collaborations with several world leaders in material science, including Professor Michael Hoffmann from the California Institute of Technology; Professor Guozhong Cao from the University of Washington; Professors Takayoshi Sasaki, Jinhua Ye and Dr Kiyoshi Ozawa from the National Institute for Materials Sciences, Japan; Professor Michael Wark from Ruhr-University Bochum, Germany; and Professors Huiming Cheng, Yingchun Zhu and Can Li from the Chinese Academy of Sciences.

    Memberships, patents and funding

    As a chief investigator, Professor Wang has secured 13 ARC grants, two CSIRO Flagship Cluster projects, major Queensland Government funding, a CRC project and a number of UQ grants, totaling more than $12 million. He is co-author of 13 patents for new materials for clean energy use. Professor Wang is a member of the American Chemical Society, Institute of Chemical Engineers (IChemE) and the Australian Nanotechnology Network.

    Awards and plenaries

    Additional to Professor Wang’s ARC Future Fellowship and QEII awards, he has received the STA Fellowship of Japan; UQ Research Excellence Award; and Scopus Young Researcher Award in the Engineering and Technology category. He has delivered more than 30 plenary and invited keynote presentations at international conferences and symposia.

    Key publications

    LZ Wang, T. Sasaki, Titanium Oxide Nanosheets: Graphene Analogues with Versatile Functionalities, Chemical Reviews, 2014, 114, 9455-9486.

    X. Zong, H. J. Chen, B. Seger, T. Pedersen, M. Dargusch, E. McFarland, C. Li, LZ Wang, Selective production of hydrogen peroxide and oxidation of hydrogen sulfide in an unbiased solar photoelectrochemical cell, Energy Environ. Sci., 2014, 7, 3347-3351. (selected as back cover)

    Y. Chen, DL. Ye, M. Wu, H.R. Chen, L. Zhang, J. L. Shi, LZ Wang, Break-up of two-dimensional MnO2 nanosheets promotes ultrasensitive pH-triggered theranostics of cancer, Adv. Mater., 2014, DOI: 10.1002/adma.201402572.

    DL. Ye, K. Ozawa, B. Wang, D. Hulicova-Jurcakova, J. Zou, CH Sun, LZ Wang, Capacity-controllable Li-rich cathode materials for lithium-ion batteries, Nano Energy, 2014, 6, 92-102.

    X. Zong, JF Han, B. Seger, HJ Chen, GQ Lu, Can Li, LZ Wang, An integrated Photoelectrochemical −Chemical Loop for Solar-driven Overall H2S Splitting, Angew. Chem. Int. Ed., 2014, 126, 4488-4492. (highlighted by C&E News and ChemViews) .

    B Seger, J McCray, A Mukherji, X Zong, Z Xing, LZ Wang, An n-Type to p-Type Switchable Photoelectrode Assembled from Alternating Exfoliated Titania Nanosheets and Polyaniline Layers, Angew. Chem. Int.  Ed. 2013, 52, 6400-6403.

    Y Bai, H Yu, Z Li, GQ Lu, R Amal, LZ Wang, In Situ Growth of a ZnO Nanowire Network within a TiO2 Nanoparticle Film for Enhanced Dye-Sensitized Solar Cell Performance, Advanced Materials, 2012, 24, 5850-5856.

    Mukherji, B. Seger, GQ Lu, LZ Wang, Nitrogen Doped Sr2Ta2O7 Coupled with Graphene Sheets as Photocatalysts for Increased Photocatalytic Hydrogen Production,  ACS Nano, 2011, 5 (5), pp 3483–3492

    X. Wu, GQ Lu, LZ Wang, Shell-in-Shell TiO2 Hollow Spheres Synthesized by One-Pot Hydrothermal Method for Dye-Sensitized Solar Cell Application, Energy and Environmental Science, 2011, 4, 3565-3572.

    A Mukherji, R. Marschall, A. Tanksale, CH Sun, S. Smith, GQ Lu, LZ Wang,  N-doped CsTaWO6 as a New Photocatalyst for Hydrogen Production from Water Splitting under Solar Irradiation, Advanced Functional Materials, 2011, 21(1), 126-132. (Frontispiece, highlighted in Nature Photonics, 2011, Vol.5, 265.)

    Recent publications

    Full list of publications available at UQ eSpace.

  • Professor Andrew Whittaker

    BSc (Hons) UQ, PhD UQ
    ARC Australian Professorial Fellow and Group Leader


    Telephone: +61 7 334 63885 Email: a.whittaker@uq.edu.au

    Research: Polymer chemistry, nanotechnology, photolithography, biomaterials science, magnetic resonance

    Professor Andrew Whittaker's research aims to develop innovative solutions to major health and nanotechnology challenges. He is an Australian Research Council (ARC) Australian Professorial Fellow, a Fellow of the Royal Australian Chemical Institute and the International Union of Pure and Applied Chemistry and a member of the ARC College of Experts. He directs research funded through more than $52 million in competitive grants since 2002. Professor Whittaker’s work in synthesis and characterisation of polymeric materials has underpinned major development programs in several key areas. In the field of materials for photolithography this has been supported by funding from leading semiconductor companies Intel, Sematech and the Dow Chemical Company. Outcomes include novel high-index resists for 193nm immersion lithography, new concepts for design of non-chemically amplified resists for EUV lithography, and more recently novel approaches to healing roughness in IC features. In the field of biomaterials science, Professor Whittaker is most active in developing novel imaging agents for MRI, and introduced a new class of 19F polymeric agents. He is an expert in the fundamentals of diffusion process in complex solids. He has an international reputation in the field of NMR and MRI of polymeric systems.

    International links

    Professor Whittaker is a member of numerous international committees of governing bodies in polymer science and technology, and is involved in organising major international conferences. He is past-president of the Pacific Polymer Federation. He has active collaborations with scientists at Nagoya Institute of Technology (NIT), Japan; Hubei University, Shanghai University, Fudan University, National Center for Nanoscience and Technology, China; the University of Nottingham, UK; IMEC, Belgium; Dow Electronic Materials, US; and the Intel Corporation, USA. He is currently a visiting professor at Hubei University, and has held visiting professor positions at INSA Lyon and NIT and was DICE Chair at University of Nottingham.

    Awards and plenaries

    Professor Whittaker has been plenary, keynote or invited speaker at many international conferences including within the past 18 months years plenary speaker at the International Conference on Innovation in Polymer Science and Technology 2013, October 2013, Yogyakarta; the 13th Pacific Polymer Conference, November 2013, Kaohsiung; Polychar 2014, April 2014, Stellenbosch; Nanomedicine 2014, July 2014, Sydney. Professor Whittaker has been the recipient of numerous awards, including the RACI Polymer Division Citation (1998), the RACI Polymer Division Polymer Science and Technology Achievement Award (2000), an ARC Australian Professorial Fellowship in 2011, the World Famous Scientists Lecturing in Hubei Project (2013), the National High-end Foreign Experts Recruitment Project of the PRC (twice, in 2013 and 2014), the Paul J. Florey Polymer Research Prize for excellence in polymer research by the Polychar World Forum (2014), and the President’s International Fellowship (Visiting Scientist) of the Chinese Academy of Sciences (2015).

    Recent Publications

    UQ eSpace List of Publications by Professor Andrew Whittaker

    Xie, Fengwei, Flanagan, Bernadine M., Li, Ming, Sangwan, Parveen, Truss, Rowan W., Halley, Peter J., Strounina, Ekaterina V., Whittaker, Andrew K., Gidley, Michael J., Dean, Katherine M., Shamshina, Julia L., Rogers, Robin D. and McNally, Tony (2014) Characteristics of starch-based films plasticised by glycerol and by the ionic liquid 1-ethyl-3-methylimidazolium acetate: a comparative study. Carbohydrate Polymers, 111 841-848. PDF

    Pearce, Amanda K., Rolfe, Barbara E., Russell, Pamela J., Tse, Brian W.-C., Whittaker, Andrew K., Fuchs, Adrian V. and Thurecht, Kristofer J. (2014) Development of a polymer theranostic for prostate cancer. Polymer Chemistry, . PDF

    Zhang C., Peng H. and Whittaker A.K. (2014) NMR investigation of effect of dissolved salts on the thermoresponsive behavior of oligo(ethylene glycol)-methacrylate-based polymers. Journal of Polymer Science, Part A: Polymer Chemistry, 52 16: 2375-2385. PDF

    Ardana, Aditya, Whittaker, Andrew K. and Thurecht, Kristofer J. (2014) PEG-based hyperbranched polymer theranostics: optimizing chemistries for improved bioconjugation. Macromolecules, 47 15: 5211-5219. PDF

    Zhang H., Zhou L., Noonan O., Martin D.J., Whittaker A.K. and Yu C. (2014) Tailoring the void size of iron oxide@carbon yolk-shell structure for optimized lithium storage. Advanced Functional Materials, 24 27: 4337-4342. PDF

    Santander-Borrego, Miriem, Green, David W., Chirila, Traian V., Whittaker, Andrew K. and Blakey, Idriss (2014) Click functionalization of methacrylate-based hydrogels and their cellular response. Journal of Polymer Science Part A: Polymer Chemistry, 52 13: 1781-1789. PDF

    Ooi H.W., Cooper S.J., Huang C.-Y., Jennins D., Chung E., Maeji N.J. and Whittaker A.K. (2014) Coordination complexes as molecular glue for immobilization of antibodies on cyclic olefin copolymer surfaces. Analytical Biochemistry, 456 1: 6-13. PDF

    Al Abdulla, Wael A., Hill, David J. T. and Whittaker, Andrew K. (2014) Photodegradation of some low-density polyethylene-montmorillonite nanocomposites containing an oligomeric compatibilizer. Journal of Applied Polymer Science, 131 18: . PDF

    Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2014) Biodegradable core crosslinked star polymer nanoparticles as 19F MRI contrast agents for selective imaging. Polymer Chemistry, 5 5: 1760-1771. PDF

    Rolfe, Barbara E., Blakey, Idriss, Squires, Oliver, Peng, Hui, Boase, Nathan R. B., Alexander, Cameron, Parsons, Peter G., Boyle, Glen M., Whittaker, Andrew K. and Thurecht, Kristofer J. (2014) Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo. Journal of the American Chemical Society, 136 6: 2413-2419. PDF

    Yan, Kai, Li, Huan, Wang, Xin, Yi, Changfeng, Zhang, Quanyuan, Xu, Zushun, Xu, Haibo and Whittaker, Andrew K. (2014) Self-assembled magnetic luminescent hybrid micelles containing rare earth Eu for dual-modality MR and optical imaging. Journal of Materials Chemistry B, 2 5: 546-555. PDF

    Keen, Imelda, Cheng, Han-Hao, Yu, Anguang, Jack, Kevin S., Younkin, Todd R., Leeson, Michael J., Whittaker, Andrew K. and Blakey, Idriss (2014) Behavior of lamellar forming block copolymers under nanoconfinement: implications for topography directed self-assembly of sub-10 nm structures. Macromolecules, 47 1: 276-283. PDF

    Wang, David K., Varanasi, Srinivas, Strounina, Ekaterina, Hill, David J. T., Symons, Anne L., Whittaker, Andrew K. and Rasoul, Firas (2014) Synthesis and characterization of a novel POSS-PEG macromonomer and POSS-PEG-PLA hydrogels for periodontal applications. Biomacromolecules, 15 2: 666-679. PDF

    Ooi, Huey Wen, Peng, Hui, Jack, Kevin S. and Whittaker, Andrew K. (2014) Understanding the diffusion of dextrans in 'Click' PNIPAAm hydrogels. Australian Journal of Chemistry, 67 1: 85-92. PDF

    Wang, David K., Varanasi, Srinivas, Fredericks, Peter M., Hill, David J. T., Symons, Anne L., Whittaker, Andrew K. and Rasoul, Firas (2013) FT-IR characterization and hydrolysis of PLA-PEG-PLA based copolyester hydrogels with short PLA segments and a cytocompatibility study. Journal of Polymer Science Part A: Polymer Chemistry, 51 24: 5163-5176. PDF

    Ooi, Huey Wen, Jack, Kevin S., Peng, Hui and Whittaker, Andrew K. (2013) "Click" PNIPAAm hydrogels - a comprehensive study of structure and properties. Polymer Chemistry, 4 17: 4788-4800. PDF

    Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2013) pH-responsive star polymer nanoparticles: potential F-19 MRI contrast agents for tumour-selective imaging. Polymer Chemistry, 4 16: 4480-4489. PDF

    Ooi, Huey Wen, Jack, Kevin S., Whittaker, Andrew K. and Peng, Hui (2013) Photo-initiated thiol-ene "click" hydrogels from RAFT-synthesized poly(N-isopropylacrylamide). Journal of Polymer Science. Part A, Polymer Chemistry, 51 21: 4626-4636. PDF

    Dargaville, Bronwin L., Vaquette, Cedryck, Rasoul, Firas, Cooper-White, Justin J., Campbell, Julie H. and Whittaker, Andrew K. (2013) Electrospinning and crosslinking of low-molecular-weight poly(trimethylene carbonate-co-L-lactide) as an elastomeric scaffold for vascular engineering. Acta Biomaterialia, 9 6: 6885-6897. PDF

  • Professor Ernst Wolvetang

    BSc (Hons) U Amsterdam, PhD U Amsterdam
    Group Leader


    Telephone: +61 7 334 63894 Email: e.wolvetang@uq.edu.au

    Research: Induced pluripotent stem cells, in vitro disease models, novel regenerative medicine approaches

    Professor Ernst Wolvetang is leading the derivation of footprint-free induced pluripotent stem cells (iPSC) in Australia, with a particular focus on neuronal and cardiac disease models. He is the inaugural director of the collaborative reprogramming network Cell Reprogramming Australia and organises the only annual Australian iPSC workshop. Professor Wolvetang is a chief investigator at the Australian Research Council’s Special Research Initiative in Stem Cell Science, Stem Cells Australia and two National Health and Medical Research Council (NHMRC) project grants (2013-2015).

    International links

    Professor Wolvetang has international collaborations with the University of Dammam, Saudi Arabia; Utrecht University, The Netherlands; The University of Copenhagen, Denmark; and the National University of Singapore.

    Memberships, patents and funding

    Professor Wolvetang serves on the editorial board of six stem cell journals; is listed inventor on four patents in stem cell research; and is the recipient of more than $2.5 million in grant funding in the past five years. He is a senior reprogramming scientist in Stem Cells Ltd, chaired the Genetic Stability of Stem Cells session at the 2007 International Society for Stem Cell Research (ISSCR) conference in Cairns and organizes, among others, the Frontiers in Reprogramming conference.

    Make a difference to Professor Wolvetang's research by donating today.

    Awards and plenaries

    Professor Wolvetang has given 25 lectures and was invited speaker at 23 platform meetings, including two keynote addresses. He spoke at the International Society for Stem Cell Research (ISSCR) conference in Toronto, Canada in 2006; and the 2nd Annual World Congress of Regenerative Medicine & Stem Cell in Dalian, China in 2009. Professor Wolvetang organised a master-class on iPS cells at The 2nd Annual World Stem Cells & Regenerative Medicine Congress in Seoul, Korea in 2010.

    Key publications for the past five years

    Wolvetang E, Herszfeld D, Langton-Bunker E, Chung T, Filipczyk A, Houssami S, Koh K, Laslett AL, Michalska A, Nguyen L, Reubinoff BE, Tellis I, Auerbach JM, Ording CJ, Looijenga LHJ, Pera MF. (2006) CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells. Nat Biotech 24(3), 351-357.

    Chung T-L, Brena RM, Kolle G, Grimmond SM, Berman BP, Laird PW, Pera MF, Wolvetang EJ. (2010) Vitamin C promotes widespread yet specific demethylation of the hESC epigenome. Stem Cells 28(10), 1848-1855.

    Chen YS, Pelekanos RA, Ellis RL, Horne R, Wolvetang EJ, Fisk NM. (2011) Small Molecule Mesengenic Induction of Human Induced Pluripotent Stem Cells to Generate Mesenchymal Stem/ Stromal Cells. Stem cells Translational Medicine 1, 83-95.

    Nayler SP, Gatei M, Kozlov S, Gatti R, Mar JC, Wells CA, Lavin M, Wolvetang EJ. (2012) Induced pluripotent stem cells from ataxia-telangiectasia recapitulate the cellular phenotype. Stem cells Translational Medicine 1, 523-535.

    Briggs JA, Sun J, Shepherd J, Ovchinnikov DA, Chung TL, Nayler SP, Kao LP, Morrow CA, Thakar NY, Soo SY, Peura T, Grimmond SM, Wolvetang EJ. (2012) Integration-free iPS cells identify genetic and neural developmental features of Down syndrome etiology. Stem Cells 31(3), 467-478.

    Briggs JA, Mason E, Ovchinnikov DA, Wells CA, Wolvetang EJ. (2012) New paradigms for Down syndrome research using iPSCs: tackling complex human genetic disease. Stem Cells Translational Medicine 2(3), 175-184.

  • Professor Michael Yu

    BSc ECNU, PhD Fudan
    Vice-Chancellor’s Research Focused Fellow and Group Leader


    Telephone: +61 7 3346 3283 Email: c.yu@uq.edu.au

    Research: Applied functional nanomaterials

    Professor Chengzhong (Michael) Yu is an internationally recognised expert in materials science. He is an Australian Research Council (ARC) Future Fellow. 

    International links

    Professor Yu has collaborations with scientists in chemistry, material science and chemical engineering from the US, Japan, Scotland, Sweden, France and China. Through these collaborations, more than 30 international journal papers have been published.

    Memberships, patents and funding

    Professor Yu has attracted five Discovery Projects, two Linkage Projects and two Linkage Infrastructure Equipment and Facilities grants from the ARC, and grants from from the Cancer Council Queensland; Queensland Government, Cotton Research and Development Corporation and other funding agencies. He has undertaken a number of collaborative projects with commercial partners. Before he joined AIBN in 2010, he attracted 12 grants from the National Science Foundation of China; the Chinese Ministry of Science and Technology; the Chinese Education Ministry; and Shanghai Government. Professor Yu is a referee for more than 50 international journals. He is a reviewer for the ARC and NHMRC; and a grants peer review panel member for the NHMRC in 2012.

    Awards and plenaries

    Professor Yu is an ARC Future Fellow (2009). He is the recipient of the 2015 Le Févre Memorial Prize for Chemistry (The Australian Academy of Science), 2015 UQ Vice-Chancellor’s Research Focused Fellowship, 2009 Innovation Award of the Chemistry Academy of China; the 2009 Young Scientist Award of the Ceramic Society of China; the 2005 New Century Scientist Award from the Chinese Ministry of Education; and the 2004 Young Scientist Award from the Chemistry Academy of China. Professor Yu received the National Excellent Doctoral Dissertation Award in China (2004); the second prize of the National Science Award of China (2004); and the Shanghai Science & Technology Progress Award (2002). He has been invited to give more than 30 plenary, keynote and invited talks.

    Key publications for the past five years

    1. Song H, Ahmad Nor Y, Yu MH, Yang YN, Zhang J, Zhang HW, Xu C, Mitter N, Yu CZ. (2016) Silica Nano-Pollens Enhance Adhesion for Long-Term Bacterial Inhibition. J. Am. Chem. Soc., DOI: 10.1021/jacs.6b00243.
    2. Zhang HW, Noonan O, Huang XD, Yang YN, Xu C, Zhou L, Yu CZ. (2016) Surfactant-Free Assembly of Mesoporous Carbon Hollow Spheres with Large Tunable Pore Sizes. ACS Nano, DOI: 10.1021/acsnano.6b00723.
    3. Yang YN, Stefano B, Song H, Zhang J, Yu MH, James R, Ekaterina S, Debra S, Yu CZ. (2016) Anion Assisted Synthesis of Large Pore Hollow Dendritic Mesoporous Organosilica Nanoparticles: Understanding the Composition Gradient. Chem. Mater. DOI: 10.1021/acs.chemmater.5b03963.
    4. Ahmad Nor Y, Niu YT, Karmakar S, Zhou L, Xu C, Zhang J, Zhang HW, Yu MH, Mahony D, Mitter N, Cooper M, Yu CZ. (2015) Shaping Nanoparticles with Hydrophilic Compositions and Hydrophobic Properties as Nanocarriers for Antibiotic Delivery. ACS Cent. Sci., 1, 6, 328-334.
    5. Zhang HW, Yu MH, Song H, Noonan O, Zhang J, Yang YN, Zhou L, Yu CZ. (2015) Self-organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-free Sequential Heterogeneous Nucleation Pathway. Chem. Mater. 27, 18, 6297-6304.
    6. Yang J, Zhang HW, Yu MH, Emmanuelawati I, Zou J, Yuan ZG, Yu CZ. (2014) High-content, Well-dispersed γ-Fe2O3 Nanoparticles Encapsulated in Macroporous Silica with Superior Arsenic Removal Performance. Adv. Funct. Mater. 24(10), 1354–1363.
    7. Zhang HW, Zhou L, Noonan O, Martin DJ, Whittaker AK, Yu CZ. (2014) Tailoring the Void Size of Iron Oxide@Carbon Yolk-Shell Structure for Optimized Lithium Storage. Adv. Funct. Mater. 24(27), 4337–4342.
    8. Niu YT, Yu MH, Hartono SB, Yang J, Xu HY, Zhang HW, Zhang J, Zou J, Dexter A, Gu WY, Yu CZ. (2013) Nanoparticles mimicking viral surface topography for enhanced cellular delivery. Adv Mater, 25 43: 6233-6237.
    9. Jarnbhrunkar S, Yu MH, Yang J, Zhang J, Shrotri A, Endo-Munoz L, Moreau J, Lu GQ, Yu CZ. (2013) Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision. J. Am. Chem. Soc. 135 23: 8444-8447.
    10. Huang XD, Qian K, Yang J, Zhang J, Li L, Yu CZ, Zhao DY. (2012) Functional Nanoporous Graphene Foams with Controlled Pore Sizes. Adv. Mater. 32, 4419–4423.

    Recent publications

    Full list of publications available at UQ eSpace.

  • Professor Kirill Alexandrov

    PhD EMBL
    ARC Future Fellow and Group Leader


    Telephone: +61 7 3346 2017 Email: k.alexandrov@imb.uq.edu.au

    Research: Next-generation technologies for protein research

    Professor Kirill Alexandrov is a co-founder of successful biotechnology company Jena Bioscience and credited with establishing the Dortmund Protein Production Facility at the Max-Planck Institute. He introduced high−throughput molecular cloning technology to the UQ Protein Expression Facility. Professor Alexandrov has secured three Australian Research Council (ARC) and two National Health and Medical Research Council (NHMRC) project and program grants since 2008; and been awarded an ARC Australian Postdoctoral Fellowship and Future Fellowship.

    International links

    Professor Alexandrov is a co-founder of successful biotechnology company Jena Bioscience and has retained close collaborative links with the Dortmund Protein Production Facility at the Max-Planck Institute. He has close collaborations with Brisbane biotechnology company Bioproton LLC and Perth biotechnology company Phylogica.

    Memberships, patents and funding

    Professor Alexandrov has raised about $22 million in funding since 2008; secured three Australian Research Council and two National Health (ARC) and Medical Research Council (NHMRC) grants since 2008; and been awarded an ARC Australian Postdoctoral Fellowship and Future Fellowship. He filed six patents, including one which has reached international phase.

    Awards and plenaries

    Professor Alexandrov has received more than 30 invitations to speak at national and international conferences. They include:

    • 2011 PepTalk, US. Invited Plenary Speaker, Chair of round table discussion
    • 2011 9th Matsuyama International Symposium on Cell-Free Sciences, Japan. Invited Plenary Speaker
    • 2011 FASEB Summer Research Conferences on Protein Lipidation, Signaling, and Membrane Domains, US. Invited Plenary Speaker
    • 2011 Choroideremia disease Workshop, France. Invited Plenary Speaker
    • 2011 9th Australian Peptide Conference, Australia. Invited Plenary Speaker

    In 2004, Professor Alexandrov was awarded Germany’s highest career development fellowship, the Heisenberg Award.

    Key publications in the past five years

    Stein V. and Alexandrov K. Protease-based synthetic sensing and signal amplification. PNAS, 2014 In press,  Accepted 26.09.2014

    Kovtun O., Tillu VA., Jung WR., Leneva N., Ariotti N., Chaudhary N.,Mandyam RA, Ferguson C., Harrop SJ., Alexandrov K., Parton RG and Collins BM. Structural insights into the organisation of the cavin membrane coat complex. Dev. Cell. In press. Accepted 03.10.2014

    Martin S, Papadopulos A, Tomatis VM, Sierecki E, Malintan NT, Gormal RS, Giles N, Johnston WA, Alexandrov K, Gambin Y, Collins BM, Meunier FA.  Increased polyubiquitination and proteasomal degradation of a munc18-1 disease-linked mutant causes temperature-sensitive defect in exocytosis.  Cell Rep. 2014 Oct 9;9(1):206-18

    Tnimov Z, Abankwa D, Alexandrov K. RhoGDI facilitates geranylgeranyltransferase-I-mediated RhoA prenylation. Biochem Biophys Res Commun. 2014 Oct 3;452(4):967-73. Kovtun O, Mureev S, Jung W, Kubala MH, Johnston W, Alexandrov K. (2011) Leishmania cell-free protein expression system. Methods 55(1), 58-64.

    Kovtun O, Mureev S, Johnston W, Alexandrov K. (2010) Towards the construction of expressed proteomes using a Leishmania tarentolae based cell-free expression system. PLOS One 5, e14388.

    Mureev S, Kovtun O, Nguyen UTT, Alexandrov K. (2009) Species-independent translational leaders enable the rapid development of novel cell-free expression systems. Nature Biotechnology 27, 747-752.

    *Joint appointment with UQ’s Institute for Molecular Biosciences. Visit Professor Alexandrov's IMB site here.

  • Associate Professor Zhi Ping (Gordon) Xu

    BSc and MSc USTC, China; MSc NUS, Singapore; PhD NUS, Singapore
    ARC Future Fellow and Associate Group Leader


    Telephone: +61 7 3346 3809 Email: gordonxu@uq.edu.au

    Research: Clay nanomaterials for drug delivery and vaccines

    Professor Zhi Ping (Gordon) Xu is an Australian Research Council (ARC) Future Fellow (2013-2016). Since 2004, He has received a number of fellowships and awards, including an ARC Australian Postdoctoral Fellowship (2005-2007), ARC Australian Research Fellowship (2008-2012), and UQ Foundation’s Research Excellence Award (2009). Professor Xu and his colleagues have received funding from the ARC and National Health and Medical Research Council (NHMRC) totalling more than $5 million. Professor Xu is an ARC and NHMRC referee.

    Visit Professor Xu's site at UQ's Nanomaterials Centre here.

    Key publications

    Gu Z, Rolfe BE, Xu ZP, Campbell JH, Lu GQ, Thomas AC. (2012) Antibody-targeted drug delivery to injured arteries using layered double hydroxide nanoparticles. Adv Healthcare Mater 1, 669-673.

    Zhu Y, Li Z, Chen M, Cooper H, Lu GQ, Xu ZP. (2012) Synthesis of robust sandwich-like SiO2@CdTe@SiO2 fluorescent nanoparticles for cellular imaging. Chem Mater 24, 421-423.

    Li P, Xu ZP, Hampton MA, Vu DT, Huang LB, Rudolph V, Nguyen AV. (2012) Control Preparation of Zinc Hydroxide Nitrate Nanocrystals and Examination of the Chemical and Structural Stability. J Phys Chem C 116, 10325-10332.

    Xu ZP, Niebert M, Porazik K, Walker TL, Cooper HM, Middelberg APJ, Gray PP, Bartlett PF, Lu GQ. (2008) Subcellular compartment targeting of layered double hydroxide nanoparticles. J Control Release 130, 86-94.

    Gu Z, Thomas A, Xu ZP, Campbell J, Lu GQ. (2008) In vitro sustained release of low molecular weight heparin from MgAl-layered double hydroxide nanohybrids. Chem Mater 20, 3715-3722.

    Recent publications

    Full list of publications available at UQ eSpace.

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