AIBN Seminar Series Life without macrophages. The impacts of CSF1R mutations in mice and rats

We are pleased to present Professor David Hume to present Life without macrophages. The impacts of CSF1R mutations in mice and rats.

When: Thursday 23rd May 

Where: AIBN Level 1 Seminar room or online via zoom click here to join.

Time: 11am-12pm

Abstract

Macrophages have been ascribed many functions in embryonic and postnatal development based upon the impacts of experimental macrophage depletion or conditional mutation of macrophage-expressed transcripts.  The development of macrophages depends upon signals from the macrophage colony stimulating factor receptor (CSF1R).  This talk will highlight the limited impacts on organogenesis and development of the congenital macrophage deficiency associated with CSF1R mutations.

Bio

Professor David Hume received his PhD in Biochemistry from the Australian National University in 1979.  He has been an NHMRC Professorial Research Fellow at the Mater Research Institute-UQ since 2018 and was previously Director of The Roslin Institute at the University of Edinburgh (2007-2017).  David has authored over 450 scientific publications and has supervised more than 60 PhD graduates. He is an international authority in genome sciences and transcriptomics and was a leading member of the FANTOM Consortium from 2000-2017.  His ongoing research has a particular focus on the function of macrophages in development, physiology and regenerative medicine and on transcriptional regulation of macrophage differentiation (see www.macrophagelab.org).