Alexandre’s research focuses on the regulation of mitochondrial dynamics and function during confined cancer cell migration.

My research aims to elucidate the complex crosstalk between cellular energy demands, mitochondrial positioning, and cytoskeletal mechanics in cells navigating challenging environments. My goal is to contributing to our understanding of cancer cell metastasis and identify potential therapeutic interventions.

Key Publications

Mechanical confinement induces ferroptosis through mitochondrial dysfunction F Zhou, RJ. Ju, C Kang, J Li, A Yang, A Libert, ... BioRxiv 2024