Microfluidics-Based Microgels, Granular Hydrogels, Polymer Science, and Soft Robotics
Microgels derived from natural or synthetic hydrogels have attracted considerable attention as versatile carriers for cells and drugs, holding great promise in tissue engineering and regenerative medicine. Granular hydrogels, formed through the bottom-up assembly of microgels, represent a novel class of microporous platforms for cell culture and delivery. The overarching aim of Changjiang Liu’s PhD work is to develop innovative fabrication strategies—such as radical-free and surfactant-free methods—to minimize cytotoxicity during preparation, expand the biomedical applications of cell-laden microgels, and elucidate how their microscale properties influence biomedical outcomes. 2017–2021, Sun Yat-Sen University, China. Bachelor of Engineering in Biomedical Engineering. 2021–2024, Sun Yat-Sen University, China. Master of Engineering in Biomedical Engineering. 2024–2025, Sun Yat-Sen University and The Hong Kong University of Science and Technology (GZ), China. Research Assistant. 2025–present, The University of Queensland, Australia. PhD Candidate.
Key Publications
Liu, C.; Han, J.; Li, Z.; Liu, Y.; Wu, R.; Cao, S.; Wu, D. Imidazolium-Based Main-Chain Copolymers With Alternating Sequences for Broad-Spectrum Bactericidal Activity and Eradication of Bacterial Biofilms. Macromol. Biosci. 2024, 24 (5), 2300489.
Liu, C.; Cui, B.; Huang, X.; Zheng, X. (Rayne); Vo-Doan, T. T.; Qiao, R. 3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends. Adv. Robot. Res. e202500076.
Liu, Y.; Liu, C.; Xue, Y.; Han, J.; Tang, J.; Wu, D.; Liu, J. Hydrophilic Porphyrin-Cationic Fluorene Conjugated Polymer Enhances Antibacterial Photodynamic Therapy for Bacterial Biofilm Destruction. Chem. Mater. 2025, 37 (15), 5946–5959.
Duan, Z.; Liu, C.; Tang, J.; Zhang, R.; Peng, D.; Lu, R.; Cao, Z.; Wu, D. Fluorinated Hydrogel Nanoparticles with Regulable Fluorine Contents and T2 Relaxation Times as 19F MRI Contrast Agents. RSC Adv. 2023, 13 (32), 22335–22345.
Han, J.; Duan, Z.; Liu, C.; Liu, Y.; Zhao, X.; Wang, B.; Cao, S.; Wu, D. Hyperbranched Polymeric 19F MRI Contrast Agents with Long T2 Relaxation Time Based on β-Cyclodextrin and Phosphorycholine. Biomacromolecules 2024, 25 (9), 5860–5872.