Sarthak’s research focuses on using brain organoids to study the relationship between demyelination and cellular senescence in multiple sclerosis.
Sarthak is working on a brain organoid model that integrates myelinated axons and immune cells (microglia) within the same system. He is leveraging this model to explore the mechanisms underlying neuroinflammation, particularly in demyelinating diseases like multiple sclerosis. His research mainly aims to understand the role of cellular senescence in MS pathology.