Sin-Wei Huang

Development of Targeted mRNA-LNP Therapeutics for Cancer

Sin-Wei Huang graduated from National Taiwan University with a major in Microbiology and Immunology. After receiving his master’s degree, he worked as a research assistant at Academia Sinica. During that time, he published several papers, including one first-author paper and multiple co-authored publications. He later joined a biotechnology start-up focused on developing multifunctional protein therapeutics for cancer and metabolic diseases. He is now pursuing his PhD at the Australian Institute for Bioengineering and Nanotechnology (AIBN) at The University of Queensland, where he is working on developing targeted mRNA-LNP therapeutics for cancer.

Key Publications

Overcoming the nutritional immunity by engineering iron-scavenging bacteria for cancer therapy.

Bacteria colonization in tumor microenvironment creates a favorable niche for immunogenic chemotherapy.

Tri-functional High-affinity Superantigen-based Multivalent Immune Cell Engager Synergizes NK and T Cell Activation for Tumor Suppression.

Improvement of Gene Delivery by Minimal Bacteriophage Particles.

Targeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy