Nanotechnology, Drug delivery, colorectal cancer

​Currently working on Oral delivery of targeted micelles for colorectal cancer therapeutics. Colorectal cancer (CRC) is the third leading cause of cancer related morbidity and mortality worldwide. Chemotherapy is not as effective as other cancer in case of CRC. Oral delivery of chemotherapeutics may open a new treatment concept "Chemotherapy at home." The aim of the project is to synthesis an amphiphilic block copolymer which selfassemble into nano size micells that incorprated hydrophobic anticancer drug . Then the micelles were encapsulate into microcapsule to facilitate the oral delivery. In vitro cell uptake showed targeted micelles had better uptake than the untargeted micelles. In vivo biodistribution studies reflects the nanocarrier is suitable for oral delivery.

​Dewan Taslima Akhter is a PhD student , Thurecht polymer group at Australian Institute of Bioengineering and Nanotechnology (AIBN), University of Queensland. She is currently working on "Oral delivery of targeted micelles for colorectal cancer therapeutics".She had completed her MS in Pharmaceutical Science and B.Pharm( Hons) from Jahangirnagar University, Bangladesh. She received Government University Merit Scholarship and also University Grant Commission (UGC) scholarship for her outstankding results in B.Pharm(Hons) and Masters. She started her career as a Pharmacist. Then she started her career in Academia as a Lecturer in Stamford University Bangladesh and as a Senior Lecturer, East West University Bangladesh. She got Australian Government Research Training Program (RTP) Scholarship/UQcent to persue her Doctor of Philosophy (PhD) at University of Queensland.

Key Publications

​Dewan Taslima Akhter, Riaz Uddin, Naz H Huda, Kumar B Sutradhar. Design and formulation of twice daily Nifedipine sustained release tablet using Methocel K15M CR and Methocel K100LV CR. International Journal of Pharmacy and Pharmaceutical Sciences, 2012; 4(1): 121-124

Dewan Taslima Akhter, Riaz Uddin, Kumar B Sutradhar, Md. Sohel Rana. In vitro Relese Kinetic Study of Ambroxol hydrochloride Sustained Release Matrix Tablets Using Hydrophilic and Hydrophobic Polymers. Journal of Chemical and Pharmaceutical Research, 2012; 4(3):1573-1579

Dewan Taslima Akhter, Riaz Uddin, Dilshad Yasmin, Rajia Sultana Nijhu. Calcium and vitamin D related knowledge in 16-18 years old adolescents:Does living in urban or rural areas matter? Life Sciences: Journal of Nutrition and Food Sciences ,2013;3(6):240

Rajia Sultana Nijhu, Dewan Taslima Akhter, Yeakuty Marzan Jhanker. Development and validation of UV spectrophotometric method for quantitative estimation of nitroglycerin in pharmaceutical dosage form, International Current Pharmaceutical Journal, 2011; 1(1):1-5

Kumar B Sutradhar, Dewan Taslima Akhter, Riaz Uddin. Formulation and evaluation of taste mask orodispersible tablet of Domperidone using sublimation method . International Journal of Pharmacy and Pharmaceutical Sciences, 2012; 4 (2):727-732

Funding

​Australian Government Research Training Program (RTP) Scholarship/UQcent