Bioengineering Biosensors for Infectious Disease Diagnosis

 Supervisor Dr Christopher Howard

The project will focus on the development of innovative diagnostic reagents for the detection of infectious diseases using protein bioengineering and yeast based bionanomaterial systems. Molecules targeting the Sars Cov2 spike protein and surface proteins of Influenza virus will be fused with sensory and reporter protein elements to build an “all in one” viral sensor. The project will utilise molecular biology, protein design and engineering and bionanomaterial characterisation.

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Building yeast based bionanomaterials as diagnostic, vaccine and therapeutic platforms

 Supervisor Dr Christopher Howard

The project will focus on the development of yeast bionanomaterials as a platform for the display of proteins for application as potential diagnostics, vaccines or therapeutics. Anchor proteins displayed on the surface of yeast will be genetically modified to display the spike/envelope proteins of Sars Cov2, influenza and other pathogenic viruses. Yeast based bionanomaterials will be developed and tested for functional binding to virus targets and potential ability to induce antibody responses. The project will utilise aspects of molecular biology, protein design and engineering and bionanomaterial characterisation.
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What to do

  1. Review each project description and find one which matches your areas of interest.
  2. Contact the project advisor directly to discuss the project and arrange a meeting or visit to the AIBN lab.

Contact 

AIBN Engagement Officer
aibn.events@uq.edu.au
07 334 64215

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