Development of affordable and effective nanomaterial-based approaches for sensitive detection of biomolecules

Dr Chang Lei has published a total of 23 papers, 1 book chapter and 1 patent, 8 of which have a FWCI above 1.0. and two papers are in the top 10% of most cited articles worldwide in their subject area. During her PhD study, she was awarded two scholarships and an outstanding award. She is now an Advance Queensland Research Fellow.

Industry Engagement and Collaborations

Dr Chang Lei is working on projects under industrial collaboration with Ellume Pty Ltd (AU).

Dr Lei has had collaborations with several Universities, such as East China University of Science and Technology and Nanjing University of Science and Technology.​


2019     Advance Qld Women’s Research Assistance Program.

2019     UQ Amplify grant, The University of Queensland, Australia.

2017     Advanced Queensland Research Fellow (early career), Australia.

Key Publications

Kalantari, M.; Ghosh, T.; Liu, Y.; Zhang, J.; Zou, J.; Lei, C.* (corresponding author); Yu, C. Z*. Highly-thiolated Dendritic Mesoporous Silica Nanoparticles with High-content Gold as Nanozyme: The Nano-Gold Size Matters. ACS Appl. Mater. Interfaces, 2019, 11, 14, 13264-13272.

Li, H. M.; Guo, H. L.; Lei, C.; Liu, L.; Xu, L.Q.; Feng, Y. P.; Ke, J.; Fang, W.; Song, H.; Xu, C.; Yu, C. Z.; Long, X. Nanotherapy in joints: increasing endogenous hyaluronan production by delivering hyaluronan synthase 2. Adv Mater, 2019, (Cover story)

Lei, C.; Xu, C.; Nouwens, A.; Yu, C. Z. Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles. J. Mater. Chem. B, 2016, 4, 4975-4979.

Lei, C.; Xu, C.; Noonan, O.; Zhang, L.; Nouwens, A.; Yu, C. Z. Mesoporous Materials Modified by Aptamers and Hydrophobic Groups Assist Ultra-sensitive Insulin Detection in Serum. Chem Commun, 2015, 51, 13642 – 13645.

Lei, C.; Noonan, O.; Jambhrunkara, S.; Qian, K.; Xu, C.; Zhang, J.; Nouwens, A.; Yu, C. Z. Sensitive Detection of Human Insulin Using a Designed Combined Pore Approach. Small, 2014, 10 (12), 2413-2418.

Featured projects Duration
Sensitive Detection of Biomolecules