Development of affordable and effective nanomaterial-based approaches for sensitive detection of biomolecules

Dr Chang Lei has published a total of 14 papers with an impact factor of 65, with six of those papers being first author and three of them being second author. She has two patents in the area of ultrasensitive biomarker detection and nano-platform development. During her PhD study, she was awarded two scholarships and an outstanding award. She is now an Advance Queensland Research Fellow.

Industry Engagement and Collaborations

Dr Chang Lei is working on projects under industrial collaboration with Ellume Pty Ltd (AU).

Dr Lei has had collaborations with several Universities, such as East China University of Science and Technology and Nanjing University of Science and Technology.​


2017 Advance Queensland Research Fellowship
2015 Chinese Government Award for Outstanding Self-financed Students Abroad
2014 University of Queensland International Scholarship (UQI)
2012 University of Queensland International Scholarship (UQI)
2006~2009 Honour student scholarship of Wuhan University
2007-2008 Wuhan University Undergraduate Research & innovative grant

Key Publications

  1. Lei, C; Xu, C; Nouwens, A; Yu, C. Z. Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles. J. Mater. Chem. B, 2016, 4, 4975-4979. (IF 4.872)
  2. Lei, C; Zhou, L.; Xu, C; Sun, X. R; Nouwens, A; Yu, C. Z. Binder-free TiO2 Monolith Packed Pipette-tips for the Enrichment of Phosphorylated Peptides. Aust J Chem, 2016, (IF 1.427)
  3. Lei, C.; Xu, C.; Noonan, O.; Zhang, L.; Nouwens, A.; Yu, C. Z. Mesoporous Materials Modified by Aptamers and Hydrophobic Groups Assist Ultra-sensitive Insulin Detection in Serum. Chem Commun, 2015, 51, 13642 – 13645. (IF 6.834)
  4. Lei, C.; Noonan, O.; Jambhrunkara, S.; Qian, K.; Xu, C.; Zhang, J.; Nouwens, A.; Yu, C. Z. Sensitive Detection of Human Insulin Using a Designed Combined Pore Approach. Small, 2014, 10(12), 2413-2418. (IF 8.368)
  5. Lei, C.; Qian, K.; Noonan, O.; Nouwens, A.; Yu, C. Z. Applications of Nanomaterials in Mass Spectrometry Analysis. Nanoscale, 2013, 5 (24), 12033 - 12042. (IF 7.394)
Featured projects Duration
Sensitive Detection of Biomolecules