Project Summary

Biomolecules with clinical significance are most often various forms of proteins or peptides at very low concentrations in biological systems. Quantitative analysis of them is a big challenge due to the complexity of bio-samples, but essential for diagnosis and clinical applications. In this project, we focus on developing novel approaches for the sensitive detection of trace amount biomolecules using state-of-the-art nanotechnology.

Imaging of stamped invisible micro-patterns of trace amount molecules.
Imaging of stamped invisible micro-patterns of trace amount molecules.


Research Group

Yu Group


Nanomaterials, Nanobiotechnology, Health, Mass spectrometry, Enrichment, Biomarkers, Detection, Biomolecules

Available Student Projects

Sensitive Detection of Human Insulin using a Designed Combo-Pore Approach

Mesoporous Materials Modified by Aptamers and Hydrophobic Groups Assist Ultra-sensitive Insulin Detection in Serum

Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

Pore Size-Optimized Periodic Mesoporous Organosilicas for Enrichment of Peptides and Polymers

Laser Engineered Graphene Paper for Mass Spectrometry Imaging


Project members

Lead Investigator

Professor Chengzhong (Michael) Yu

Senior Group Leader
Yu Group


Dr Chang Lei

UQ Amplify Researcher
Yu Group