Designed synthesis of silica nanoparticles as nano-carriers for bio-applications.

In recent decades, the efficient delivery of large molecules has drawn extensive attention. Limited by the poor stability and cell-membrane impermeability of large biomolecules, delivery vehicles are highly desired to immobilize the molecules and improve their delivery efficiency. Yue Wang is devoted in the designed synthesis of MSNs with tailored structure and improved therapeutic performance in bio-applications.

Yue Wang obtained the Bachelor degree in bio-engineering at Tianjin University in 2014. In 2016, she completed the MPhil study at the University of Queensland in biomedical engineering under the supervision of Prof. Chengzhong Yu. She is currently a PhD student in Prof. Chengzhong Yu’s group at the University of Queensland. She is devoted in the designed synthesis of nanomaterials with tailored structure for improved delivery efficiency of large biomolecules in bio-applications.

Key Publications

  1. Yue Wang, Jie Tang, Yannan Yang, Hao Song, Jianye Fu, Zhengying Gu and Chengzhong Yu*, Functional nanoparticles with a reducible tetrasulfide motif upregulate messenger RNA translation and enhance transfection in hard-to-transfect cells, Angewandte Chemie, 2019, DOI: 10.1002/anie.201914264 and 10.1002/ange.201914264
  2. Yue Wang, Yannan Yang, Yiru Shi, Hao Song* and Chengzhong Yu*, Antibiotic-free Antibacterial strategies enabled by Nanomaterials: Progress and Perspectives, Advanced Materials,2019, DOI: 10.1002/adma.201904106
  3. Yue Wang, Hao Song, Yannan Yang, Yang Liu, Jie Tang and Chengzhong Yu*, Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling, Chemistry of Materials, 2018, 30, 5770-5776
  4. Yue Wang, Hao Song, Meihua Yu, Chun Xu, Yang Liu, Jie Tang, Yannan Yang and Chengzhong Yu*, Room Temperature Synthesis of Dendritic Mesoporous Silica Nanoparticles with Small Sizes and Enhanced mRNA delivery Performance, Journal of Materials Chemistry B, 2018, 6, 4089-4095
  5. Yue Wang, Yusilawati Ahmad Nor, Hao Song, Yannan Yang, Chun Xu, Meihua Yu and Chengzhong Yu*, Small-sized and large-pore dendritic mesoporous silica nanoparticles enhanced antimicrobial enzyme delivery, Journal of Materials Chemistry B, 2016, 4, 2646-2653
  6. Jiao Wang; Yue Wang; Qiang Liu; Linnan Yang; Rongrong Zhu; Chengzhong Yu* and Shilong Wang*, Rational Design of Multifunctional Dendritic Mesoporous Silica Nanoparticles to Load Curcumin and Enhance Efficacy for Breast Cancer Therapy, ACS Applied Materials & Interfaces, 2016, 8, 40, 26511-26523
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Nanotechnology for Sustainability