Bioinformatics

As a bioinformatician with a background in both biochemistry and software development it is the role of Dr Robin Palfreyman to support the group, the wider university community and external clients with their bioinformatics requirements. He is responsible for the analysis, manipulation, interpretation and integration of a variety of large datasets such as omics related data including genomic, transcriptomic, proteomic and metabolomic data. He provides bioinformatics support through Q-MAP, the Queensland node of Metabolomics Australia. Overall Dr Palfreyman enables those he works with to gain a better understanding of the organism they are studying thus allowing them to engineer their processes of interest.

Collaborations

Q-MAP: Queensland Metabolics and proteomics qmap.org.au

Key Publications

Barry CP; Gillane R; Talbo GH; Plan M; Palfreyman R; Haber-Stuk AK; Power J; Nielsen LK; Marcellin E (2022), Multi-omic characterisation of Streptomyces hygroscopicus NRRL 30439: detailed assessment of its secondary metabolic potential. Molecular Omics, 18(3):226-236, DOI: 10.1039/d1mo00150g

Gomes de Oliveira Dal'Molin C; Quek LE; Saa PA; Palfreyman R; Nielsen LK (2018), From reconstruction to C4 metabolic engineering: A case study for overproduction of polyhydroxybutyrate in bioenergy grasses. Plant Science 273:50-60, DOI: 10.1016/j.plantsci.2018.03.027

Vogl T, Gebbie L, Palfreyman RW, Speight R (2018), Effect of plasmid design and type of integration event on recombinant protein expression in Pichia pastoris. Appl Environ Microbiol. 84(6): e02712-17, DOI: 10.1128/aem.02712-17

Marcellin, Esteban, Behrendorff, James B., Nagaraju, Shilpa, DeTissera, Sashini, Segovia, Simon, Palfreyman, Robin W., Daniell, James, Licona-Cassani, Cuauhtemoc, Quek, Lake-ee, Speight, Robert, Hodson, Mark P., Simpson, Sean D., Mitchell, Wayne P., Kopke, Michael and Nielsen, Lars K. (2016)
Low carbon fuels and commodity chemicals from waste gases-systematic approach to understand energy metabolism in a model acetogen.
Green Chemistry, 18 10: 3020-3028.
doi:10.1039/c5gc02708j

Dal'Molin, C.G.D., Quek, L.E., Palfreyman, R.W., Brumbley, S.M. and Nielsen, L.K. (2010)
AraGEM, a Genome-scale reconstruction of the primary metabolic network in arabidopsis.
Plant Physiology, 152 2: 579-589.
doi:10.1104/pp.109.148817