Elucidating the impact of micro-exon splicing defects in autism spectrum disorder (ASD) with human iPSC-derived brain organoids

Pallavi Gupta is currently working with the Wolvetang group, working on a thesis titled 'Elucidating the impact of micro-exon splicing defects in autism spectrum disorder (ASD) with human iPSC-derived brain organoids'.

Collaborations and industry engagement

The project is a collaboration between the University of Queensland and the Indian Institute of Technology, Delhi as a part of the UQ - IITD Academy of Research (UQIDAR) joint PhD program. The host lab at IITD under Prof. Ishaan Gupta works in the field of functional genomics and bioinformatics.

Key publications

  1. Bhatia, S., Makhija, Y., Jayaswal, S., Singh, S., Malik, P.S., Venigalla, S.K., Gupta, P., Samaga, S.N., Hota, R.N. and Gupta, I., 2022. Severity and mortality prediction models to triage Indian COVID-19 patients. PLOS Digital Health, 1(3), p.e0000020.
  2. Jayaswal, S.K., Singh, S., Malik, P.S., Venigalla, S.K., Gupta, P., Samaga, S.N., Hota, R.N., Bhatia, S.S. and Gupta, I., 2021. Detrimental effect of diabetes and hypertension on the severity and mortality of COVID-19 infection: A multi-center case-control study from India. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 15(5), p.102248.
  3. Gupta, I., Dandavate, R., Gupta, P., Agarwal, V. and Kapoor, M., 2020. Recent advances in genetic studies of alcohol use disorders. Current genetic medicine reports, 8(2), pp.27-34.