Project Summary

Polyisocyanopeptide (PIC)-based hydrogel functionalised with tri-ethylene glycol is an ideal scaffold for wound healing approaches as it is a liquid that solidifies at body temperature enabling easy application to complex wound sites and their mechanical responsiveness mimics that of biopolymers. This project is focused on using PIC hydrogel as the matrix for therapeutic wound dressings and by conjugation of bioactive molecules, promote wound healing by bringing about hemostasis as well as disinfection and stimulation of subsequent healing.

Immune Synapse Formation
Bio-functionalised polyisocyanopetide based hydrogel for use in hemostasis (blood coagulation) the first stage of wound healing.

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Project members

Lead Investigator

Professor Alan Rowan

AIBN Institute Director
Senior Group Leader
Rowan Group

Dr Amanda Wraith Kijas

Senior Research Fellow
Rowan Group

Researchers Involved

Dr Jan Lauko

Centre Manager
Advanced Spinifex Biofutures Materials Centre

External to AIBN

Dr Lambro Johnson, Dr Paul Masci, Professor John de Jersey, Professor Martin Lavin, Dr Kong-Nan Zhao.