With the rapid increase in population and economy, the demand for food has increased dramatically. The use of antibiotics to control bacterial and virus diseases is restricted in the livestock. Vaccination is widely used to manage livestock diseases in farm industry. However, most commercial vaccines are injected subcutaneously, which causes stress of the animals and cross-infections, makes vaccination difficult for your stock with insensitive manpower. Oral vaccination with antigen included in feed would be the ideal method for vaccination, especially for poultry and fish. Thus, the aim of this project is to design and make a cost-effective nanoplatform with commercial vaccine antigens in animal feed to enhance immune response for animal health control.