Weiyu Chen Specialises in applied nanomedicine: immune response, pathogenic Escherichia coli and clay nanoparticles.

In recent decades, diseases caused by pathogenic Escherichia coli have been increasingly reported worldwide, which are required effective intervention strategies. Clay nanoparticles have provided new tools to enhance the systemic immunogenicity as adjuvants via their versatile properties, enabling them to be broadly employed in medical and clinical studies. My researh is focusing on the application of two representatives of clay nanoparticles, layered double hydroxide (LDH) nanoparticles and Laponite (hectorite) as nano-adjuvant in stimulating immune response, against pathogenic Escherichia coli . Current studies have shown great potential of these two clay nanopartilces as potent nano-adjuvant in boosting efficient immune response and protection against invasion of pathogenic Escherichia, which are even better than that mediated by commercial adjuvants.​  

Weiyu Chen is a​​ PhD student in Australian Institute for Bioengineering & Nanotechnology (AIBN), the University of Queensland. He received the bachelor and master degree from Xiamen University, China before he joined Xu group in AIBN. Currently, his research focuses on applying clay nanoparticles as nano-adjuvants to induce immune response against pathogenic Escherichia E. coli.​

Key Publications

Chen WY, Zhang B, Mahony T, Gu WY, Rolfe B, Xu ZP. Efficient and Durable Vaccine against Intimin beta of Diarrheagenic E-Coli Induced by Clay Nanoparticles. Small. 2016;12:1627-39.​

Current Research Projects