Dr Mostafa Kamal Masud

Dr. Masud specializes in the design and fabrication of novel nanostructures as well as nano-diagnostic technologies for the early detection of chronic (e.g., cancer) and infectious disease

Dr. Masud considers himself as an emergent research leader with research capability in the field of medical nanotechnology and personalised nanodiagnostics in Australia. His research focuses on the development of novel nanostructures and nano-diagnostic technologies to address critical issues in medical diagnostics and treatment monitoring. He pioneered the development of biosensing techniques based on mesoporous nanostructures for detecting clinically important biomarkers (e.g., microRNA, exosome, and autoantibody) that have paved the way for the development of point-of-care diagnostics for diseases. His research received attention in the research community and was highlighted in local and international media (Griffith News “gold! Griffith finds a cheap way to detect cancer”, UQ News “Pot of gold engineered to help with early disease detection”; Phys.Org “Detecting Cancer Just Got Cheaper; etc.). The quality of his research is demonstrated by the award of a prestigious Dean's Award for Outstanding Higher Degree by Research Theses 2020 by the University of Queensland, Australia; Japan Society for the Promotion of Science (JSPS) Postdoctoral fellowship (2020) at NIMS, Japan; Australia-Japan Foundation (AJF) Grant (2022-23) from the University of Queensland, Australia; Postgraduate Research Award (2018-2020) from AINSE Limited, Sydney, Australia; International Travel Award (2020) from AIBN, UQ; Outstanding Poster Prize (2018) from AINSE/ANBUG Neutron Scattering Symposium; and RSC Analytical Method Poster Prize from 21st Australia and New Zealand Electrochemistry Symposium 2019. He is actively involved in peer-review of prestigious journals in the filed and serving as an Editorial Board Member (Biology and Biomedicine Section) of “Micromachines”.

Dr. Masud is a Postdoctoral Research Fellow at the Australian Institute for Bioengineering & Nanotechnology (AIBN), the University of Queensland (UQ). In 2020, he received his PhD in Medical Biotechnology Diagnostics and Nanobiotechnology from AIBN, UQ. After completing his PhD, he was awarded a prestigious JSPS Postdoctoral Fellowship (success rate >10%) from Japan and served as a Postdoctoral Fellow at Japan's National Institute for Materials Science (NIMS). As an early career researcher (2 years to post PhD), he has attained an excellent track record with 40 peer-reviewed publications (13 as a first author; 5 as a corresponding author) in prestigious and high-impact journals (e.g. ACS Nano, Small, Biosensor and Bioelectronics, Chemical Society Review, Analytical Chemistry, Sensors and Actuators B, Chemical Communication, Journal of Material Chemistry B, etc.) in the area that achieve <1600 citations with an h-index of 21 (Scholar google link: https://bit.ly/2Vtv67l). He has developed new classes of superparamagnetic nanostructures and fabricated novel biosensors for the detection of disease-specific biomarkers that have proven to be easy and effective, allowing for rapid diagnosis with minimal equipment. He made a major contribution to nanotechnology integrated-analytical and diagnostic fields by providing analytical and technological input as well as developing key collaborations with clinicians and biologists for translational research. His strategy is to create nano-architecture point-of-care diagnostic technology for early diagnosis of cancer that could hopefully lead to a healthy and happier life for humans.

Collaborations

• Centre for Clinical Research- UQCCR, The University of Queensland (UQ), Brisbane, Australia
• Translational Research Institute-TRI, UQ, Brisbane, Australia
• Queensland Micro- and Nanotechnology Centre (QMNC), Griffith University, Brisbane, Australia
• School of Materials Science and Engineering, University of New South Wales (UNSW), Sydney, Australia
• National Institute for Materials Science-NIMS, Japan
• Center for Bio-Integrated Electronics, Northwestern University, USA
• National Centre for Catalysis Research, Indian Institute of Technology Madras, India.
• Shahjalal University of Science and Technology, Sylhet-3114, Bangladesh.

Industry

​AINSE, Australian Nuclear Science and Technology Organisation (ANSTO), New Illawarra Rd, Lucas Heights NSW 2234.

Key publications:

1. Nishat, Z.S., Hossain, T., Islam, M.N., Phan, H.P., Wahab, M.A., Moni, M.A., Salomon, C., Amin, M.A., Sina, A.A.I., Hossain, M.S.A., Kaneti, Y.V., Yamauchi, Y. and Masud, M.K.,* Hydrogel Nanoarchitectonics: An Evolving Paradigm for Ultrasensitive Biosensing. Small, 2022, 2107571. (*Corresponding author)
2. Wahab, M.A., Hossain, S.A., Masud, M.K.,* Park, H., Ashok, A., Mustapić, M., Kim, M., Patel, D., Shahbazi, M., Hossain, M.S.A. and Yamauchi, Y., Nanoarchitectured superparamagnetic iron oxide-doped mesoporous carbon nanozymes for glucose sensing. Sensors and Actuators B: Chemical, 2022, 366,131980.
3. Masud, M.K., Na, J., Lin, T.-E., Malgras, V., Preet, A., Sina, A.A.I., Wood, K., Billah, M., Kim, J., You, J., Kani, K., Whitten, A., Nguyen, N.-T., Shiddiky, M.J.A., Trau, M., Hossain, M.S.A. and Yamauchi, Y. Mesoporous Gold Biosensor for Electrochemical Detection of Attomolar MicroRNA, Biosensors and Bioelectronics, 2020, 112429.
4. Phan H.P, Zhong Y, Nguyen T.K, Park Y, Dinh T, Song E, Vadivelu R.K, Masud M.K, Li J., Shiddiky M.J.A., Dao D. Yusuke, Y., Rogers, J.A. and Nguyen, N.T., Long-Lived, Transferred Crystalline Silicon Carbide Nanomembranes for Implantable Flexible Electronics, ACS Nano, 2019, 13, 11572-11581.
5. Masud, M.K, Younus M, Hossain, M.S.A, Bando Y, Shiddiky, M.J, and Yamauchi Y, Superparamagnetic Nanoarchitectures for Disease-Specific Biomarker Detection, Chemical Society Review, 2019, 48, 5717-5751.
6. Masud, M.K., Billah, M.M., Kim, J., Wood, K., Shiddiky, M.J.A., Nguyen, N.T., Parsapur, R.K., Selvam, P., Hossain, M.S.A., and Yamauchi, Y., Nanoarchitectured peroxidase-mimetic nanozymes: mesoporous nanocrystalline α- or γ-iron oxide?, Journal of Material Chemistry B, 2019, 7, 5412-22.
7. Boriachek, K., Masud, M.K., Palma, C., Phan, H.P., Yamauchi, Y., Hossain, M.S.A., Nguyen, N.T., Salomon, C. and Shiddiky, M.J.A., Avoiding Pre-Isolation Step in Exosome Analysis: Direct Isolation and Sensitive Detection of Exosomes Using Gold-Loaded Nanoporous Ferric Oxide Nanozymes. Analytical Chemistry, 2019, 89, 11005-11013.
8. Masud, M.K., Yadav, S., Islam, M.N., Nguyen, N.T., Salomon, C., Kline, R., Alamri, H.R., Alothman, Z.A., Yamauchi, Y., Hossain, M.S.A. and Shiddiky, M.J.A., Gold-Loaded Nanoporous Ferric Oxide Nanocubes with Peroxidase-Mimicking Activity for Electrocatalytic and Colorimetric Detection of Autoantibody, Analytical Chemistry, 2017, 89, 11005-11013.
9. Masud, M.K., Islam, M.N., Haque, M.H., Tanaka, S., Gopalan, V., ALICI, G., Nguyen, N.T., Lam, A.K.Y., Hossain, M.S., Yamauchi, Y. and Shiddiky, M.J.A., Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA, Chemical Communications, 2017, 53, 8231-8234.
10. Yadav, S., Masud, M.K., Islam, M.N., Gopalan, V., Lam, A.K., Tanaka, S., Nguyen, N.T., Hossain, M.S., Li, C., Yamauchi, Y. and Shiddiky, M.J.A., Gold-Loaded Nanoporous Iron Oxide Nanocubes: A Novel Dispersible Capture Agent for Tumor-Associated Autoantibodies Analysis in Serum, Nanoscale, 2017, 9, 8805-8814.