Material Science and nanotechnology: hybrid nanomaterials and biomedical applications

​Dr Ruirui Qiao's research focuses on the development of polymeric/inorganic nanocomposites and assemblies for disease diagnosis and drug delivery. The Group has developed multiple inorganic nanohybrids and assemblies including polymer grafted iron oxide, upcoversion nanoparticles, and liquid metal composites as imaging probes in magnetic resonance imaging (MRI), optical imaging, and positron emission tomography (PET) imaging for the detection of cancer, cardiovascular disease and amyloidosis. The Group has also been working with industry partners and collaborators on the clinical translation of magnetic tracers for sentinel lymph node mapping.

​Dr. Ruirui Qiao is a Group Leader and NHMRC Emerging Leadership fellow at Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland. She received her BSc (2005) and MSc (2007) in pharmaceutical science in Peking University in China. From 2007 to 2016, she worked as a research assistant and associate in Institute of Chemistry, Chinese Academy of Science (CAS). In 2016, she was promoted to be an associated Professor in Chinese Academy of Sciences. In 2017, she joined Monash Institute of Pharmaceutical Sciences (MIPS) as a research fellow within ARC Centre of Bio-Nano Science (CBNS) under the leadership and mentorship of Professor Tom Davis. In 2019, she relocated to AIBN as the co-project leader of CBNS. Her research focuses on the development of polymeric/inorganic nanohybrids and assemblies for disease diagnosis and therapy.  Dr Ruirui Qiao's research has attactracted over $1.5 M funding from various funding sources in Australia, Germany and China. She was invited to University of Muenster as a visiting scholar sponsored by DAAD. She's currently serving as the associate editor for Journal of Bionanotechnology and guest editor for several journals.

Industry

Dr Ruirui Qiao has established a joint industry/academic project Ferronova, Pty Ltd (NHMRC Dev Grant) for the clinical translation of biocompatible magnetic tracers for sentinel lymph nodes detection.

Collaborations

​She has built extensive collaborations with scientists in world-leading research institutes and universities (University of Birmingham, University of Science and Technology of China, Zhejiang University, and University of Wisconsin–Madison, etc.)

Key Publications

Ruirui Qiao, Changkui Fu, Yuhuan Li, Xiaole Qi, Dalong Ni, Aparna Nandakumar, Ghizal Siddiqui, Haiyan Wang, Zheng Zhang, Tingting Wu, Jian Zhong, Shi‐Yang Tang, Shuaijun Pan, Cheng Zhang, Michael R Whittaker, Jonathan W Engle, Darren J Creek, Frank Caruso, Pu Chun Ke, Weibo Cai, Andrew K Whittaker, Thomas P Davis, Sulfoxide‐Containing Polymer‐Coated Nanoparticles Demonstrate Minimal Protein Fouling and Improved Blood Circulation, Advanced Science, 2020, 7, 2000406.

Fangyun Xin, Yuhuan Li, Changkui Fu, Ibrahim Javed, Xumin Huang, Anaïs Schaschkow, Rita S Garcia Ribeiro, Esteban N Gurzov, Thomas P Davis, Xiaoling Zhang*, Pu Chun Ke, Ruirui Qiao, Multimodal Nanoprobe for Pancreatic Beta Cell Detection and Amyloidosis Mitigation, Chemistry of Materials, 2020, 32, 3, 1080–1088. 

Yuhuan Li, Fangyun Xin, Jinming Hu, Shweta Jagdale, Thomas P Davis, Christoph E Hagemeyer, Ruirui Qiao, Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis, Polymer Chemistry, 2020, 11, 1010 - 1017. (Emerging Investigators 2020 collection)

Ruirui Qiao, Hongyu Qiao, Yan Zhang, Yabin Wang, Chongwei Chi, Jie Tian, Lifang Zhang, Feng Cao and Mingyuan Gao, Molecular Imaging of Vulnerable Atherosclerotic Plaques in vivo with Osteopontin-Specific Upconversion Nanoprobes, ACS Nano, 2017, 11(2), 1816-1825. 

Ruirui Qiao, Changhao Liu, Muhan Liu, Hao Hu, Chunyan Liu, Yi Hou, Kaichun Wu, Yenan Lin, Jimin Liang, Mingyuan Gao, Ultrasensitive in Vivo Detection of Primary Gastric Tumor and Lymphatic Metastasis Using Upconversion Nanoparticles, ACS Nano, 2015, 9(2), 2120–2129.

Full list of publications available on espace

Funding

​Dr Ruirui Qiao has been the recipient of NHMRC investigator grant and has secured more than $1.5 million from various funding sources including NHMRC, Advance Queensland, NSFC and DAAD.