Project Summary

Day 45 organoids stained with DAPI (blue) and MAP2 (green). ​

This project focuses on deciphering the contributions of intrinsic (cell autonomous) drivers in ageing-related bone loss associated with osteoporosis. Our studies aim to provide the necessary foundation data for understanding the underlying fundamental roles of molecular drivers in osteoporosis onset and progression and ultimately, to develop a novel potential therapeutic target centred on altering these drivers to rescue osteoporotic bone loss in vitro and in vivo.

Research Group



Rebecca Griffiths, Justin Cooper-White, Ernst Wolvetang

Project members

Lead Investigator

Researchers Involved

Professor Ernst J. Wolvetang

Senior Group Leader
Wolvetang Group
UQ-StemCARE Director