Project summary

Immunotherapy is an active and exciting research area that shows promising outcomes for cancer disease regression. In general, immunotherapy involves stimulating our immune system to identify and eliminate foreign bodies (e.g., virus, bacteria, etc.) or tumour cells residing within our bodies. An important aspect of assessing the efficacy of immunotherapy relies on evaluating a patient's immune status at different time points —i.e., before, during and after treatment. This project aims to develop microfluidic biosensors using state-of-art microfabrication techniques for the isolation and characterisation of immune cells. This interdisciplinary project will provide an opportunity for students to acquire diverse skills in oncology, molecular biology, nanofabrication, and microfluidics.

A typical example of a microfluidic device for cancer cell phenotyping (For details, see ACS Sensors 1(4), 399-405)

 

Research Group

Trau Group

Keywords

Microfluidic Device, microfabrication, cancer cells, immune cells,  Electrochemistry

Available Student Projects

SERS Microfluidic Assay for Cancer Biomarkers

Project members

Lead Investigator


Professor Matt Trau

Senior Group Leader
Trau Group

Researchers

Dr Alain Wuethrich

NHMRC Emerging Leadership Fellow and ARC DECRA awardee
Centre for Personalised Nanomedicine (Trau Group)