Wound healing is a dynamic process requiring a coordinated response. Cells respond to both biochemical and biophysical cues within their microenvironment, together modulating cellular responses.
Despite the remarkable ability of nanomedicines to diagnose and treat disease, activation of the immune system and the development of innate and adaptive immunity against specific subsets of nanomedicines is a significant unresolved challenge.
Targeted alpha-therapies (TATs) are emerging as powerful radiopharmaceutical tools for cancer treatment, allowing precise and localised dosing of highly potent radiotherapy.
Nanomedicine, the application of nanotechnology and biotechnology to medicine, is a rapidly expanding field of research with great promise for making meaningful changes in the way we treat many diseases including cancer.
In radiotherapeutics, a wide range of organic ligands have been designed to coordinate inorganic radioisotopes for diagnostic or therapeutic purposes. These ligands are typically conjugated to a targeting moiety through a linker; an organic bridge between the ligand and the targeting moiety.
Sequential infiltration synthesis (SIS) is becoming an important tool for formation of unique nanostructures. SIS is a variant of atomic layer deposition (ALD), in which the organometallic precursors are allowed to diffuse into the polymeric substrate before condensation.