Project Summary

Microfluidic channel made of multilayered hydrogels
Microfluidic channel made of multilayered hydrogels
This project aims to artificially reconstruct the neurovascular niche using microfluidic technologies. The platform will enable studying the blood-brain barrier – neural niche interaction ex vivo. This model will generate fundamental insights regarding how neural stem cells and their complex microenvironment interact and change during ageing. We will develop a new type of 3D microfluidics device that will serve as a model for future investigations of stem cell niches and their microenvironment. Our goal is to explore the effects of blood circulatory factors on the health of the in vitro vasculature and identify their role in vascular and neural ageing.

Research Group

UQ-StemCARE

Keywords

stem cells, microfluidics, tissue engineering, neuroscience, hydrogel

Project members

Lead Investigator


Dr Benoit G. C. Maisonneuve

Postdoctoral Research Fellow
UQ-StemCARE

Researchers Involved

Professor Justin Cooper-White

Senior Group Leader
Cooper-White Group
UQ-StemCARE Director

Professor Ernst Wolvetang

Senior Group Leader
Wolvetang Group
UQ-StemCARE Director