Dr Fahimeh Farokhinejad saw how bispecific antibodies were used for mRNA delivery in cancer therapy and vaccination, and began to ask the question, could they be adapted for diagnostics?
The current clinically approved mRNA vaccines are packaged in Lipid Nanoparticles (LNPs), and biodistribution studies show that upon injection there is significant off-target effects where most of the LNPs are taken up by local muscle cells, while a residual portion reaches the blood stream to en
COVID-19, COVID-19 variants and Influenza are critical pandemic threat pathogens and their monitoring and rapid sensitive detection in the community is vital.