By leveraging 2D and brain organoid models this projects aims to test gene therapy approaches and conduct a targeted drug screen for the currently untreatable hereditary spastic paraplegia subtype SPG56, a disease that is caused by mutations in the CYP2U1 gene.
Tiny ‘live’ brain models are being used at The University of Queensland to study a condition causing high-functioning young people with Down Syndrome to suddenly regress.
Studying tiny ‘live’ models of the human brain has helped researchers understand its ageing and find a key to potential treatments neurodegenerative diseases.
Researchers studying ageing in tiny ‘live’ models of the human brain have found a key to potential treatments for Alzheimer’s and other neurodegenerative diseases.
Improving a “trial-and-error approach’’ to epilepsy treatment is the aim of research that encompasses stem cells, artificial intelligence, brain organoids and drug screening.
New research from the Australian Institute for Bioengineering and Nanotechnology at the University of Queensland has brought us a step closer to understanding how protein clumps called amyloid plaques contribute to the death of brain cells in Alzheimer’s disease.
The Wolvetang laboratory at AIBN recently found that key areas of the brain affected in this disease can be recreated in the lab using patient-derived stem cells, and this has now been published in the journal Frontiers in Cellular Neuroscience.
