A a key signalling pathway is activated when cancer cells change shape in response to the chemotherapy drugs taxanes – giving us new clues as to how they work.
Dr Samantha Stehbens says a cell's journey through crowded tissue environments remains shrouded in mystery. In Nature Cell Biology, she may have some new answers.
The overarching aim of this research is to elucidate the molecular mechanisms that cells use to move in 3D environments: a basic biological function essential to development and homeostasis.
Extracerebral brain metastases account for 90% of all brain malignancies, outnumbering primary brain cancers.
