Membrane lipid composition influences the localisation of membrane proteins and regulates their activity. Cell membranes contain hundreds of chemically distinct lipid species that form lipid domains that impact membrane protein localisation and function.
The development of effective therapeutics that target chronic pain in neurological diseases would significantly improve the quality of life for millions of people living with chronic pain. The glycinergic neuronal transport proteins are a promising target for the treatment of chronic pain.
Biocompatible delivery systems allow enhanced delivery of pharmaceuticals, vaccines and other biological payload molecules, with varied effects including extending the pharmaceutical half-life of drugs, increasing adsorption and decreasing immunogenicity.
Multidrug resistant (MDR) infections are a global healthcare crisis. In Staphylococcus aureus and several other clinical pathogens, resistance has emerged to all classes of antimicrobial agents, including antibiotics and hospital-grade antiseptics.
Professor Megan O'Mara's research sits at the interface of chemistry, biology, physics, and computer science. Or, more simply, she uses gaming computers to solve the mysteries of the human body.
