As we close the book on 2022 it is time to look at how far the AIBN has come during the year, and how we are setting ourselves up for an even bigger 2023.
Current mRNA therapeutics and vaccines are designed for high and ubiquitously translation. However, for many mRNA drugs and gene therapies the expression of the therapeutic RNA in all cells is undesirable and translational control must be tailored to the target tissue.