Student Projects

Single-molecule detection has opened an entirely new direction in life science research. The interaction between biomolecular components within a cell is complex and dynamic, with bulk analytical methods only able to provide averaging information, typically from multi-cellular samples.

DNA vaccine shows multiple advantages over conventional live-attenuated or killed vaccines, especially in prevention against chronic infectious diseases and cancer diseases, for which traditional vaccines could not offer required cellular immunity while DNA vaccine could fulfil this demand.

​Human brain development can be severely impacted by a lack of oxygen perinatally. This project will study the molecular and cellular processes that are responsible in human stem cell derived brain organoid models.

For those interested in: Stem cell ageing and regenerative engineering

From sunscreens to vaccines, most of the modern technology we rely on today is dependent on our ability to precisely manufacture complex molecules with precise chemical properties.

Supplemental enzymes have become common additives to animal feeds. Among these enzymes, lipase aids fat digestion and subsequent improvement of feed efficiency and animal growth.

Senescnece is an important driver of ageing related brain diseases. This project will use genetic and engineered brain organoid ageing models to identify and test better and more targetd senolytics and senomorphic compounds.

The discovery of drugs that target ion channels presents a substantial opportunity for treating a wide range of medical conditions, including chronic pain, stroke, epilepsy, multiple sclerosis, and rheumatoid arthritis.

Systems that are flowing, conducting ions or electrcity, growing or changing with time are nonequilibrium systems. In fact, all real systems are out of equilbrium to some degree. Despite this, there is much to be learnt about how such systems behave at the molecular level.

Current mRNA therapeutics and vaccines are designed for high and ubiquitously translation. However, for many mRNA drugs and gene therapies the expression of the therapeutic RNA in all cells is undesirable and translational control must be tailored to the target tissue.